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KCNN4 Monoclonal antibody, PBS Only

KCNN4 Monoclonal Antibody for WB,Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rat

Applications

WB,Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2A6G5

Cat No : 60276-1-PBS

Print datasheet

Synonyms

hIKCa1, hKCa4, hSK4, IK1, IKCA1, KCa3.1, KCA4, KCNN4, Putative Gardos channel, SK4, SKCa 4, SKCa4

验证数据展示

  • WB analysis of human blood using 60276-1-Ig (same clone as 60276-1-PBS)

    WB analysis of human blood using 60276-1-Ig (same clone as 60276-1-PBS)

    human blood were subjected to SDS PAGE followed by western blot with 60276-1-Ig (KCNN4 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60276-1-PBS in a different storage buffer formulation.

产品信息

60276-1-PBS targets KCNN4 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB,Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen KCNN4 fusion protein Ag19774 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Synonyms hIKCa1, hKCa4, hSK4, IK1, IKCA1, KCa3.1, KCA4, KCNN4, Putative Gardos channel, SK4, SKCa 4, SKCa4
Calculated Molecular Weight 427 aa, 48 kDa
Observed Molecular Weight 48 kDa
GenBank Accession NumberBC015337
Gene Symbol KCNN4
Gene ID (NCBI) 3783
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDO15554
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

The intermediate conductance calcium-activated potassium channel KCNN4, also known as KCa3.1, IK1, or SK4, is a member of the potassium channel KCNN family. KCNN4 is expressed in T cells, mast cells, macrophages, erythrocytes, vascular smooth muscle cells, airway smooth muscle cells, intestinal and airway epithelial cells (PMID: 19681865; 21493782). Functionally, KCNN4 plays a key role in calcium-dependent cell functions, such as proliferation, activation, and migration, in a broad range of cell types (PMID: 21493782).