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验证数据展示

  • WB analysis of human blood using 60276-1-Ig (same clone as 60276-1-PBS)

    WB analysis of human blood using 60276-1-Ig (same clone as 60276-1-PBS)

    human blood were subjected to SDS PAGE followed by western blot with 60276-1-Ig (KCNN4 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60276-1-PBS in a different storage buffer formulation.

KCNN4 Monoclonal antibody, PBS Only

KCNN4 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 60276-1-PBS

产品说明书

CloneNo. 2A6G5

宿主/亚型

Mouse / IgG2a

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

hIKCa1, hKCa4, hSK4, IK1, IKCA1, KCa3.1, KCA4, KCNN4, Putative Gardos channel, SK4, SKCa 4, SKCa4

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

60276-1-PBS targets KCNN4 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 KCNN4 fusion protein Ag19774 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
别名 hIKCa1, hKCa4, hSK4, IK1, IKCA1, KCa3.1, KCA4, KCNN4, Putative Gardos channel, SK4, SKCa 4, SKCa4
计算分子量 427 aa, 48 kDa
观测分子量 48 kDa
GenBank蛋白编号BC015337
基因名称 KCNN4
Gene ID (NCBI) 3783
RRIDAB_2881395
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO15554
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The intermediate conductance calcium-activated potassium channel KCNN4, also known as KCa3.1, IK1, or SK4, is a member of the potassium channel KCNN family. KCNN4 is expressed in T cells, mast cells, macrophages, erythrocytes, vascular smooth muscle cells, airway smooth muscle cells, intestinal and airway epithelial cells (PMID: 19681865; 21493782). Functionally, KCNN4 plays a key role in calcium-dependent cell functions, such as proliferation, activation, and migration, in a broad range of cell types (PMID: 21493782).