验证数据展示
产品信息
66439-1-PBS targets KChIP1 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Applications | WB, IHC, IF-P, Indirect ELISA Application Description |
| Tested Reactivity | human, mouse |
| Immunogen | KChIP1 fusion protein Ag5494 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | Kv channel interacting protein 1 |
| Synonyms | KCHIP1, KCNIP1, VABP, Vesicle APC binding protein |
| Calculated Molecular Weight | 227 aa, 27 kDa |
| Observed Molecular Weight | 25 kDa |
| GenBank Accession Number | BC050375 |
| Gene Symbol | KCNIP1 |
| Gene ID (NCBI) | 30820 |
| RRID | AB_2881809 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | Q9NZI2 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Human K(v) channel interacting protein 1 (KCHIP1) is a new member of the neural calcium binding protein superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. KChIP1 is a neuronal calcium sensor protein that is predominantly expressed at GABAergic synapses and it has been related with modulation of K(+) channels, GABAergic transmission and cell death.
