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验证数据展示

  • WB analysis of human cerebellum using 66439-1-Ig (same clone as 66439-1-PBS)

    WB analysis of human cerebellum using 66439-1-Ig (same clone as 66439-1-PBS)

    human cerebellum tissue were subjected to SDS PAGE followed by western blot with 66439-1-Ig (KChIP1 antibody at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66439-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 66439-1-Ig (same clone as 66439-1-PBS)

    IHC staining of human brain using 66439-1-Ig (same clone as 66439-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 66439-1-Ig (KChIP1 antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66439-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 66439-1-Ig (same clone as 66439-1-PBS)

    IHC staining of human brain using 66439-1-Ig (same clone as 66439-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 66439-1-Ig (KChIP1 antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66439-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 66439-1-Ig (same clone as 66439-1-PBS)

    IF Staining of mouse brain using 66439-1-Ig (same clone as 66439-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using KChIP1 antibody (66439-1-Ig, Clone: 3D6C1 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66439-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 66439-1-Ig (same clone as 66439-1-PBS)

    IF Staining of mouse brain using 66439-1-Ig (same clone as 66439-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using KChIP1 antibody (66439-1-Ig, Clone: 3D6C1 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66439-1-PBS in a different storage buffer formulation.

KChIP1 Monoclonal antibody, PBS Only

KChIP1 Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA
Cat No. 66439-1-PBS

产品说明书

CloneNo. 3D6C1

宿主/亚型

Mouse / IgG1

种属反应性

human, mouse

应用

WB, IHC, IF-P, Indirect ELISA

别名

KCHIP1, KCNIP1, VABP, Vesicle APC binding protein

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66439-1-PBS targets KChIP1 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 KChIP1 fusion protein Ag5494 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 Kv channel interacting protein 1
别名 KCHIP1, KCNIP1, VABP, Vesicle APC binding protein
计算分子量 227 aa, 27 kDa
观测分子量 25 kDa
GenBank蛋白编号BC050375
基因名称 KCNIP1
Gene ID (NCBI) 30820
RRIDAB_2881809
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ9NZI2
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Human K(v) channel interacting protein 1 (KCHIP1) is a new member of the neural calcium binding protein superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. KChIP1 is a neuronal calcium sensor protein that is predominantly expressed at GABAergic synapses and it has been related with modulation of K(+) channels, GABAergic transmission and cell death.