验证数据展示
产品信息
82931-2-PBS targets KHSRP in IP, Indirect ELISA applications and shows reactivity with human samples.
Tested Applications | IP, Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | KHSRP fusion protein Ag33890 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | KH-type splicing regulatory protein |
Synonyms | KH type-splicing regulatory protein, FUSE-binding protein 2, FUBP2, FBP2, Far upstream element-binding protein 2 |
Calculated Molecular Weight | 73 kDa |
GenBank Accession Number | NM_003685 |
Gene Symbol | KHSRP |
Gene ID (NCBI) | 8570 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q92945 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
KHSRP, also named as FUBP2, KSRP, and p75, belongs to the KHSRP family. It binds to the dendritic targeting element and may play a role in mRNA trafficking. KHSRP is a part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. It mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. KHSRP may interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. It is involved in the degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.