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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • IP experiment of HeLa using 82931-2-RR (same clone as 82931-2-PBS)

    IP experiment of HeLa using 82931-2-RR (same clone as 82931-2-PBS)

    IP result of anti-KHSRP (IP:82931-2-RR, 4ug; Detection:82931-2-RR 1:2500) with HeLa cells lysate 1050 ug. This data was developed using the same antibody clone with 82931-2-PBS in a different storage buffer formulation.

  • FC experiment of U-251 using 82931-2-RR (same clone as 82931-2-PBS)

    FC experiment of U-251 using 82931-2-RR (same clone as 82931-2-PBS)

    1x10^6 U-251 cells were intracellularly stained with 0.25 ug Anti-Human KHSRP (82931-2-RR, Clone:230189C12) and APC-Conjugated Goat Anti-Rabbit IgG(H+L) (red), or 0.25 ug Rabbit IgG control Rabbit PolyAb (30000-0-AP) (blue). Cells were fixed and permeabilized with True-Nuclear Transcription Factor Buffer Set. This data was developed using the same antibody clone with 82931-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82931-2-RR

    Affinity and Kinetic Characterization of 82931-2-RR

    Biolayer interferometry (BLl) kinetic assays of 82931-2-RR against Human KHSRP were performed. The affinity constant is 1.42 nM.

KHSRP Recombinant antibody, PBS Only

KHSRP Uni-rAbTM Recombinant Antibody for IP, Indirect ELISA
Cat No. 82931-2-PBS
CloneNo. 230189C12

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IP, Indirect ELISA

Synonyms

KH type-splicing regulatory protein, FUSE-binding protein 2, FUBP2, FBP2, Far upstream element-binding protein 2

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

82931-2-PBS targets KHSRP in IP, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications IP, Indirect ELISA Application Description
Tested Reactivity human
Immunogen KHSRP fusion protein Ag33890 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name KH-type splicing regulatory protein
Synonyms KH type-splicing regulatory protein, FUSE-binding protein 2, FUBP2, FBP2, Far upstream element-binding protein 2
Calculated Molecular Weight73 kDa
GenBank Accession NumberNM_003685
Gene Symbol KHSRP
Gene ID (NCBI) 8570
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ92945
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

KHSRP, also named as FUBP2, KSRP, and p75, belongs to the KHSRP family. It binds to the dendritic targeting element and may play a role in mRNA trafficking. KHSRP is a part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. It mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. KHSRP may interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. It is involved in the degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.