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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • IP experiment of HeLa using 82931-2-RR (same clone as 82931-2-PBS)

    IP experiment of HeLa using 82931-2-RR (same clone as 82931-2-PBS)

    IP result of anti-KHSRP (IP:82931-2-RR, 4ug; Detection:82931-2-RR 1:2500) with HeLa cells lysate 1050 ug. This data was developed using the same antibody clone with 82931-2-PBS in a different storage buffer formulation.

  • FC experiment of U-251 using 82931-2-RR (same clone as 82931-2-PBS)

    FC experiment of U-251 using 82931-2-RR (same clone as 82931-2-PBS)

    1x10^6 U-251 cells were intracellularly stained with 0.25 ug Anti-Human KHSRP (82931-2-RR, Clone:230189C12) and APC-Conjugated Goat Anti-Rabbit IgG(H+L) (red), or 0.25 ug Rabbit IgG control Rabbit PolyAb (30000-0-AP) (blue). Cells were fixed and permeabilized with True-Nuclear Transcription Factor Buffer Set. This data was developed using the same antibody clone with 82931-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82931-2-RR

    Affinity and Kinetic Characterization of 82931-2-RR

    Biolayer interferometry (BLl) kinetic assays of 82931-2-RR against Human KHSRP were performed. The affinity constant is 1.42 nM.

KHSRP Recombinant antibody, PBS Only

KHSRP Uni-rAbTM Recombinant Antibody for IP, Indirect ELISA
Cat No. 82931-2-PBS

产品说明书

CloneNo. 230189C12

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IP, Indirect ELISA

别名

KH type-splicing regulatory protein, FUSE-binding protein 2, FUBP2, FBP2, Far upstream element-binding protein 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

82931-2-PBS targets KHSRP in IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IP, Indirect ELISA Application Description
经测试反应性 human
免疫原 KHSRP fusion protein Ag33890 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 KH-type splicing regulatory protein
别名 KH type-splicing regulatory protein, FUSE-binding protein 2, FUBP2, FBP2, Far upstream element-binding protein 2
计算分子量73 kDa
GenBank蛋白编号NM_003685
基因名称 KHSRP
Gene ID (NCBI) 8570
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ92945
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

KHSRP, also named as FUBP2, KSRP, and p75, belongs to the KHSRP family. It binds to the dendritic targeting element and may play a role in mRNA trafficking. KHSRP is a part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. It mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. KHSRP may interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. It is involved in the degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.