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KIAA0319L Monoclonal antibody, PBS Only

KIAA0319L Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2E11D9

Cat no : 68717-1-PBS

Print datasheet

Synonyms

KIAA0319 like, KIAA0319L, KIAA1837, PKD1 like, PP791, RP4 765A10.3

验证数据展示

  • WB analysis using 68717-1-Ig (same clone as 68717-1-PBS)

    WB analysis using 68717-1-Ig (same clone as 68717-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68717-1-Ig (KIAA0319L antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68717-1-PBS in a different storage buffer formulation.

产品信息

68717-1-PBS targets KIAA0319L in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen KIAA0319L fusion protein Ag15263 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name KIAA0319-like
Synonyms KIAA0319 like, KIAA0319L, KIAA1837, PKD1 like, PP791, RP4 765A10.3
Calculated Molecular Weight 1049 aa, 116 kDa
Observed Molecular Weight140-150 kDa
GenBank Accession NumberBC031672
Gene Symbol KIAA0319L
Gene ID (NCBI) 79932
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ8IZA0
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

KIAA0319L (also known as AAVR) is a type-I transmembrane protein that acts as a receptor for adeno-associated virus (AAV) and is involved in adeno-associated virus infection through endocytosis system (PMID: 26814968). It has been shown that KIAA0319L is highly-glycosylated and can localise to the plasma membrane, endosomes, Golgi and trans-Golgi network (TGN) (PMID: 29991750). KIAA0319L gene has been associated with susceptibility to developmental dyslexia or reading disabilities (PMID: 19085271). The predicted molecular mass of KIAA0319L is 116 kDa, but western blot detected protein at 150 kDa in lysate from HeLa cells, likely due to glycosidic linkages (PMID: 28679762; 30962536).