验证数据展示
产品信息
68235-1-PBS targets KIAA1429 in Indirect ELISA, WB applications and shows reactivity with mouse, human samples.
经测试应用 | Indirect ELISA, WB Application Description |
经测试反应性 | mouse, human |
免疫原 | KIAA1429 fusion protein Ag22449 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | KIAA1429 |
别名 | VIRMA, MSTP054, 3F1A4 |
计算分子量 | 1812 aa, 202 kDa |
观测分子量 | 200-210 kDa |
GenBank蛋白编号 | BC113380 |
基因名称 | KIAA1429 |
Gene ID (NCBI) | 25962 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q69YN4 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
VIRMA (KIAA1429) is a key component of m6A methyltransferase (writer) complex that include METTL3, METTL14, WTAP, VIRMA, HAKAI, ZC3H13, and RBM15. VIRMA mediates methylation in the 3'UTR and around the stop codon, thus affecting alternative polyadenylation. VIRMA has been reported to act as oncogenic factor in breast cancer and liver cancer.