KIDINS220 Monoclonal antibody, PBS Only

KIDINS220 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3G2D8

Cat no : 66748-1-PBS

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Synonyms

ARMS, KIAA1250, KIDINS220



产品信息

66748-1-PBS targets KIDINS220 in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen KIDINS220 fusion protein Ag17624 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name kinase D-interacting substrate, 220kDa
Synonyms ARMS, KIAA1250, KIDINS220
Calculated Molecular Weight 1672 aa, 187 kDa
Observed Molecular Weight 200 kDa
GenBank Accession NumberBC130610
Gene Symbol KIDINS220
Gene ID (NCBI) 57498
RRIDAB_2882095
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9ULH0
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Kidins220 (Kinase D-interacting substrate 220 kD) is a crucial mediator of signal transduction in neural tissues. Also it named ARMS(Ankyrin Repeat-Rich Membrane Spanning) due to the presence of ankyrin repeats and transmembrane domains together with other binding motifs. It is a multidomain transmembrane protein that not only transduces signaling mediated by the receptor tyrosine kinase (RTK), but also regulates the stability of cytoskeletal network through a number of cytoskeleton-associated proteins, including Septin5, MAPs , and stathmin family members. KIDINS220 exists some isoforms with MV 194 kDa, 185 kDa, 115 kDa, and 60 kDa.