验证数据展示
经过测试的应用
| Positive FC detected in | mouse splenocytes |
推荐稀释比
| Application | Dilution |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
FITC-65084 targets KLRG1 in FC applications and shows reactivity with Mouse samples.
| Tested Applications | FC Application Description |
| Tested Reactivity | Mouse |
| Immunogen | N/A 种属同源性预测 |
| Host / Isotype | Golden Syrian Hamster / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | killer cell lectin-like receptor subfamily G, member 1 |
| Synonyms | 2F1 Ag, Klrg1, MAFA, MAFA L |
| GenBank Accession Number | BC101953 |
| Gene Symbol | Klrg1 |
| Gene ID (NCBI) | 50928 |
| RRID | AB_3084994 |
| Conjugate | FITC Plus Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 495 nm / 524 nm |
| Form | Liquid |
| Purification Method | Affinity purification |
| UNIPROT ID | O88713 |
| Storage Buffer | PBS with 0.09% sodium azide. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
KLRG1 (killer cell lectin-like receptor subfamily G, member 1) is a C-type lectin inhibitory receptor that contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. KLRG1 is expressed by subsets of NK and T cells, existing both as a monomer and as a disulfide-linked homodimer (PMID: 10741410; 19604491). It is considered to be a cell differentiation marker for NK and T cells and is strongly induced by viral and other infections (PMID: 20373518). Through interactions with members of the cadherin family, KLRG1 plays an inhibitory role on NK- and T-cell function (PMID: 19009530; 20373518).
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for FITC Plus KLRG1 antibody FITC-65084 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |