• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84034-4-RR (same clone as 84034-4-PBS)

    WB analysis using 84034-4-RR (same clone as 84034-4-PBS)

    A549 cells were subjected to SDS PAGE followed by western blot with 84034-4-RR (L1CAM antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84034-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84034-4-RR

    Affinity and Kinetic Characterization of 84034-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84034-4-RR against Human L1CAM were performed. The affinity constant is 0.255 nM.

L1CAM Recombinant antibody, PBS Only

L1CAM Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84034-4-PBS

产品说明书

CloneNo. 240978F1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

L1 cell adhesion molecule, HSAS1, HSAS, CD171, CAML1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

Planning an IHC experiment? We recommend our IHCeasy L1CAM Ready-To-Use IHC Kit. L1CAM primary antibody included.

产品信息

84034-4-PBS targets L1CAM in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 Fusion Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 L1 cell adhesion molecule
别名 L1 cell adhesion molecule, HSAS1, HSAS, CD171, CAML1
计算分子量 1257 aa, 140 kDa
观测分子量245 kDa
GenBank蛋白编号BC126229
基因名称 L1CAM
Gene ID (NCBI) 3897
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP32004
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

L1CAM, also known as NCAM-L1 or CD171, is a cell adhesion molecule of the immunoglobulin superfamily. It is a 200-220 kDa transmembrane glycoprotein composed of six Ig-like domains and five fibronectin type III repeats followed by a transmembrane region and a highly conserved cytoplasmic tail (PMID: 3412448; 22796939). L1CAM is primarily expressed in the nervous system and is involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, cerebellar granule cell migration, neurite outgrowth on Schwann cells and interactions among epithelial cells of intestinal crypts (PMID: 3412448; 10767310). L1CAM is overexpressed in many human cancers and is often associated with bad prognosis (PMID: 27267927; 26111503).