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验证数据展示

  • WB analysis of HeLa using 66414-1-Ig (same clone as 66414-1-PBS)

    WB analysis of HeLa using 66414-1-Ig (same clone as 66414-1-PBS)

    WB result of LDLR antibody (66414-1-Ig; 1:4000; incubated at room temperature for 1.5 hours) with sh-Control and sh-LDLR transfected HeLa cells. This data was developed using the same antibody clone with 66414-1-PBS in a different storage buffer formulation.

  • WB analysis using 66414-1-Ig (same clone as 66414-1-PBS)

    WB analysis using 66414-1-Ig (same clone as 66414-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66414-1-Ig (LDLR antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66414-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 66414-1-Ig (same clone as 66414-1-PBS)

    IHC staining of human liver using 66414-1-Ig (same clone as 66414-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 66414-1-Ig (LDLR Antibody) at dilution of 1:400 (under 10x lens). This data was developed using the same antibody clone with 66414-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 66414-1-Ig (same clone as 66414-1-PBS)

    IHC staining of human liver using 66414-1-Ig (same clone as 66414-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 66414-1-Ig (LDLR Antibody) at dilution of 1:400 (under 40x lens). This data was developed using the same antibody clone with 66414-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

LDLR Monoclonal antibody, PBS Only

LDLR Monoclonal Antibody for WB, IHC, ELISA
Cat No. 66414-1-PBS

产品说明书

CloneNo. 1A2A3

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IHC, ELISA

别名

LDL receptor, FHC, FH, 1A2A3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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66414-1-Ig

产品信息

66414-1-PBS targets LDLR in WB, IHC, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 human
免疫原 LDLR fusion protein Ag1236 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 low density lipoprotein receptor
别名 LDL receptor, FHC, FH, 1A2A3
计算分子量 95 kDa
观测分子量 120 kDa, 160 kDa
GenBank蛋白编号BC014514
基因名称 LDLR
Gene ID (NCBI) 3949
ENSEMBL Gene IDENSG00000130164
RRIDAB_2881786
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP01130
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits, which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE.