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验证数据展示

  • IF Staining of human breast cancer using CL594-60066

    IF Staining of human breast cancer using CL594-60066

    Immunofluorescent analysis of (4% PFA) fixed human breast cancer tissue using CoraLite®594 LGALS3BP antibody (CL594-60066, Clone: 2D8E11 ) at dilution of 1:100.

  • IF Staining of human breast cancer using CL594-60066

    IF Staining of human breast cancer using CL594-60066

    Immunofluorescent analysis of (4% PFA) fixed human breast cancer tissue using CoraLite®594 LGALS3BP antibody (CL594-60066, Clone: 2D8E11 ) at dilution of 1:100.

CoraLite®594-conjugated LGALS3BP Monoclonal antibody

LGALS3BP Monoclonal Antibody for IF-P
Cat No. CL594-60066

产品说明书

CloneNo. 2D8E11

宿主/亚型

Mouse / IgG2b

种属反应性

human

应用

IF-P

别名

90K, BTBD17B, Galectin 3 binding protein, LGALS3BP, M2BP, Mac 2 binding protein, MAC 2 BP, MAC2BP, Tumor associated antigen 90K

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite®594
规格: 

-/ -

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经过测试的应用

Positive IF-P detected inhuman breast cancer tissue
For other applications, we recommend the unconjugated version of this antibody, 60066-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL594-60066 targets LGALS3BP in IF-P applications and shows reactivity with human samples.

经测试应用 IF-P Application Description
经测试反应性 human
免疫原 LGALS3BP fusion protein Ag0294 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 lectin, galactoside-binding, soluble, 3 binding protein
别名 90K, BTBD17B, Galectin 3 binding protein, LGALS3BP, M2BP, Mac 2 binding protein, MAC 2 BP, MAC2BP, Tumor associated antigen 90K
计算分子量 585 aa, 65 kDa
观测分子量 90 kDa
GenBank蛋白编号BC002403
基因名称 LGALS3BP
Gene ID (NCBI) 3959
RRIDAB_2919892
偶联类型 CoraLite®594 Fluorescent Dye
最大激发/发射波长588 nm / 604 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ08380
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-3-binding protein (LGALS3BP, also known as 90K or Mac-2 BP) is a secreted glycoprotein which binds galectin-3, galectin-1, beta1 integrins, collagens and fibronectin (PMID: 8034587; 8024581; 11146440; 9501082). It has been implicated in tumor metastatic processes, as well as in other cell adhesion and immune functions. Levels of LGALS3BP have been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV) (PMID: 7698018). Western analysis suggests that LGALS3BP is found in breast milk, semen, saliva, urine, and tears, in addition to serum (PMID: 8390986 ). LGALS3BP has a predicted mass of ∼65 kDa. It is heavily glycosylated and shows an apparent molecular weight of 90 kDa on SDS-PAGE.

实验方案

Product Specific Protocols
IF protocol for CL594 LGALS3BP antibody CL594-60066Download protocol
Standard Protocols
Click here to view our Standard Protocols