验证数据展示
产品信息
18278-1-PBS targets LMX1B in WB, IF, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, IF, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | LMX1B fusion protein Ag13096 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | LIM homeobox transcription factor 1, beta |
别名 | |
计算分子量 | 372 aa, 42 kDa |
观测分子量 | 42-45 kDa |
GenBank蛋白编号 | BC112120 |
基因名称 | LMX1B |
Gene ID (NCBI) | 4010 |
RRID | AB_11232226 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | O60663 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
LMX1B, LIM homeodomain factor 1b, functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Lmx1b is a continuously expressed, terminal selector-type factor in 5-HT neurons. It is required for maintenance of central serotonergic neurons (PMID: 17151281, PMID: 14602809). It is expressed in brain, testis, skeletal muscle, and pancreatic islets (PMID: 35417751, PMID: 18512225).