• Featured Product
  • KD/KO Validated

LOX Polyclonal antibody, PBS Only

LOX Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17958-1-PBS

Print datasheet

Synonyms



Planning an IHC experiment? We recommend our IHCeasy LOX Ready-To-Use IHC Kit. LOX primary antibody included.

产品信息

17958-1-PBS targets LOX in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, IP, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen LOX fusion protein Ag12479 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name lysyl oxidase
Synonyms
Calculated Molecular Weight 417 aa, 47 kDa
Observed Molecular Weight 32 kDa, 45-47 kDa
GenBank Accession NumberBC074872
Gene Symbol LOX
Gene ID (NCBI) 4015
RRIDAB_2234541
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP28300
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

LOX is a member of a multigene family (LOX, LOXL, LOXL2, LOXL3, and LOXL4). Lysyl oxidase (LOX), a copper-dependent enzyme, plays a critical role in the formation and repair of the extracellularmatrix (ECM) by catalyzing the crosslinking of elastin and collagen. LOX expression appears to be upregulated in malignancies and has recently been suggested to play a role in regulating tumor metastasis. It is synthesized as a 50 kDa proenzyme, secreted, and processed into an 32 kDa mature, active enzyme and an 18-kDa propeptide.