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验证数据展示

  • WB analysis using CL488-67139

    WB analysis using CL488-67139

    Various lysates were subjected to SDS PAGE followed by western blot with CL488-67139 (LOXL2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

CoraLite® Plus 488-conjugated LOXL2 Monoclonal antibody

LOXL2 Monoclonal Antibody for WB
Cat No. CL488-67139

产品说明书

CloneNo. 1H7F1

宿主/亚型

Mouse / IgG2a

种属反应性

Human

应用

WB

别名

LOR2, LOXL2, Lysyl oxidase homolog 2, lysyl oxidase like 2, Lysyl oxidase like protein 2, WS9 14

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -

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经过测试的应用

Positive WB detected inA549 cells, human placenta tissue
Planning an IHC experiment? We recommend our IHCeasy LOXL2 Ready-To-Use IHC Kit. LOXL2 primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-67139 targets LOXL2 in WB applications and shows reactivity with Human samples.

经测试应用 WB Application Description
经测试反应性 Human
免疫原 LOXL2 fusion protein Ag28566 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 lysyl oxidase-like 2
别名 LOR2, LOXL2, Lysyl oxidase homolog 2, lysyl oxidase like 2, Lysyl oxidase like protein 2, WS9 14
计算分子量 774 aa, 87 kDa
观测分子量 100 kDa
GenBank蛋白编号BC000594
基因名称 LOXL2
Gene ID (NCBI) 4017
RRIDAB_3084313
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9Y4K0
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

LOXL2, also named as WS9-14, belongs to an amine oxidase family whose members have been implicated in crosslink formation in stromal collagens and elastin, cell motility, and tumor development and progression. LOXL2 activity might be a crucial modulator of Snail, providing an additional control mechanism of EMT and tumor progression. Increased LOXL2 expression in colon and esophageal cancer may contribute to tumor progression. We detected a band about 100 kd which is a secretory mature LOXL2 protein modified by glycosylation (PMID: 24014025).

实验方案

Product Specific Protocols
WB protocol for CL Plus 488 LOXL2 antibody CL488-67139Download protocol
Standard Protocols
Click here to view our Standard Protocols