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验证数据展示

  • FC experiment of human PBMCs using FITC-65546

    FC experiment of human PBMCs using FITC-65546

    1x10^6 human PBMCs were surface stained with 5 ul FITC Plus Anti-Human LRP1 Rabbit Recombinant Antibody (FITC-65546, Clone:5A6), or FITC-conjugated Rabbit IgG control (FITC-30000). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

FITC Plus Anti-Human LRP1 (5A6) Rabbit IgG Recombinant Antibody

LRP1 Recombinant Antibody for FC
Cat No. FITC-65546

产品说明书

CloneNo. 5A6

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

Apolipoprotein E receptor, APOER, Alpha-2-macroglobulin receptor, Alpha 2 macroglobulin receptor, A2MR

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  FITC Plus
规格: 
25tests
100tests

¥1620/ 100tests

浓度: 5 µl/test

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经过测试的应用

Positive FC detected inhuman PBMCs

推荐稀释比

应用推荐稀释比
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl per 10^6 cells in a 100 µl suspension or 5 µl per 100 µl of whole blood.
Sample-dependent, Check data in validation data gallery.

产品信息

FITC-65546 targets LRP1 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Full length native protein (purified) 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)
别名 Apolipoprotein E receptor, APOER, Alpha-2-macroglobulin receptor, Alpha 2 macroglobulin receptor, A2MR
计算分子量 505 kDa
GenBank蛋白编号BC045107
基因名称 LRP1
Gene ID (NCBI) 4035
RRIDAB_3673870
偶联类型 FITC Plus Fluorescent Dye
最大激发/发射波长495 nm / 524 nm
形式 Liquid
纯化方式Affinity purification
储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA.
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

LRP1 (Prolow-density lipoprotein receptor-related protein 1), also known as A2MR, APOER and CD91, is a type I transmembrane protein that belongs to the LDLR family. LRP1 is synthesized as a transmembrane glycosylated precursor of 600 kDa, and is subsequently cleaved to generate a large 515-kDa N-terminal extracellular subunit and an 85-kDa C-terminal transmembrane subunit, which are noncovalently associated with one another (PMID: 2112085; 8546712). LRP1 is a multifunctional receptor involved in the clearance of a large number of diverse ligands and modulating various cellular processes. LRP1 is implicated in conditions such as atherosclerosis, cancer and neurodegenerative diseases (PMID: 28381441).

实验方案

Product Specific Protocols
FC protocol for FITC Plus LRP1 antibody FITC-65546Download protocol
Standard Protocols
Click here to view our Standard Protocols