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LSAMP Polyclonal antibody, PBS Only

LSAMP Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 13600-1-PBS

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Synonyms

验证数据展示

  • WB analysis of human brain using 13600-1-AP (same clone as 13600-1-PBS)

    WB analysis of human brain using 13600-1-AP (same clone as 13600-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 13600-1-AP (LSAMP antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13600-1-PBS in a different storage buffer formulation.

产品信息

13600-1-PBS targets LSAMP in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen LSAMP fusion protein Ag4542 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name limbic system-associated membrane protein
Synonyms
Calculated Molecular Weight 338 aa, 37 kDa
Observed Molecular Weight 64-68 kDa
GenBank Accession NumberBC033803
Gene Symbol LSAMP
Gene ID (NCBI) 4045
RRIDAB_10597712
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ13449
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

LSAMP, also known as LAMP, is a 64-68 kDa heavily glycosylated neural cell adhesion molecule expressed on the neuronal dendrites and somata (PMID: 1688937; 8666243). LSAMP is a member of the IgLON family. The amino acid sequence of LSAMP is highly conserved among species. Human LSAMP shares 99% amino acid sequence identity with rodent LSAMP. The impact of LSAMP protein on neurite outgrowth and neuronal connectivity has been established in a wide spectrum of psychiatric disorders in humans (PMID: 26136648). In mice, lack of LSAMP protein seemingly leads to a deterioration in the ability to adapt to novel stressful environments and stimuli (PMID: 22155487).