验证数据展示
产品信息
67705-1-PBS targets Laminin beta 1 in WB, Indirect ELISA applications and shows reactivity with Human, Mouse samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human, Mouse |
免疫原 | Laminin beta 1 fusion protein Ag19182 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | laminin, beta 1 |
别名 | CLM, LAMB1, Laminin 1 subunit beta, Laminin 10 subunit beta, Laminin 12 subunit beta, Laminin 2 subunit beta, Laminin 6 subunit beta, Laminin 8 subunit beta, Laminin B1 chain, Laminin beta 1, Laminin subunit beta 1, laminin, beta 1 |
计算分子量 | 1786 aa, 198 kDa |
观测分子量 | 220-240 kDa |
GenBank蛋白编号 | BC113455 |
基因名称 | Laminin beta 1 |
Gene ID (NCBI) | 3912 |
RRID | AB_2882896 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P07942 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Laminins are a family of basement membrane glycoproteins composed of three nonidentical chains, laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) (PMID: 7959779). Laminins contribute to the structure of extracellular matrix and influence the behavior of associated cells, such as adhesion, differentiation, migration, phenotype stability, and resistance to anoikis (PMID: 23057746). Laminin beta 1 (LAMB1) is expressed in most tissues that produce basement membranes, and is one of the 3 chains constituting laminin-1, the first laminin isolated from Engelbreth-Holm-Swarm (EHS) tumor. Laminin beta 1 is also a subunit of laminin-2 (laminin-211 or merosin), laminin-6 (laminin-311 or K-laminin), laminin-8 (laminin-411), laminin-10 (laminin-511) and laminin-12 (laminin-213).