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MAG Monoclonal antibody, PBS Only

MAG Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3H9G3

Cat no : 66709-1-PBS

Print datasheet

Synonyms

GMA, MAG, myelin associated glycoprotein, S MAG, SIGLEC 4A, SIGLEC4A

验证数据展示

  • WB analysis of rat brain using 66709-1-Ig (same clone as 66709-1-PBS)

    WB analysis of rat brain using 66709-1-Ig (same clone as 66709-1-PBS)

    rat brain tissue were subjected to SDS PAGE followed by western blot with 66709-1-Ig (MAG antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66709-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 66709-1-Ig (same clone as 66709-1-PBS)

    IHC staining of mouse brain using 66709-1-Ig (same clone as 66709-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66709-1-Ig (MAG antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66709-1-PBS in a different storage buffer formulation.

产品信息

66709-1-PBS targets MAG in WB, IHC, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity Human, Mouse, Rat
Immunogen MAG fusion protein Ag6065 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name myelin associated glycoprotein
Synonyms GMA, MAG, myelin associated glycoprotein, S MAG, SIGLEC 4A, SIGLEC4A
Calculated Molecular Weight 69 kDa
Observed Molecular Weight 100 kDa
GenBank Accession NumberBC053347
Gene Symbol MAG
Gene ID (NCBI) 4099
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP20916
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MAG (myelin associated glycoprotein) is a 100-kDa transmembrane glycoprotein that is a member of the SIGLEC family of proteins. MAG is localized in periaxonal Schwann cell and oligodendroglial membranes of myelin sheaths where it functions in glia-axon interactions (PMID: 17241126). It is a functional ligand for the Nogo-66 receptor (PMID: 12089450). MAG is a cell adhesion molecule for postnatal neural development and is thought to be involved in the process of myelination.