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MAGEA1 Polyclonal antibody, PBS Only

MAGEA1 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 55105-1-PBS

Print datasheet

Synonyms

验证数据展示

  • WB analysis of A375 using 55105-1-AP (same clone as 55105-1-PBS)

    WB analysis of A375 using 55105-1-AP (same clone as 55105-1-PBS)

    A375 cells were subjected to SDS PAGE followed by western blot with 55105-1-AP (MAGEA1 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55105-1-PBS in a different storage buffer formulation.

  • IF Staining of A375 using 55105-1-AP (same clone as 55105-1-PBS)

    IF Staining of A375 using 55105-1-AP (same clone as 55105-1-PBS)

    Immunofluorescent analysis of A375 cells using 55105-1-AP (MAGEA1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 55105-1-PBS in a different storage buffer formulation.

产品信息

55105-1-PBS targets MAGEA1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
Synonyms
Calculated Molecular Weight 34 kDa
Observed Molecular Weight 46 kDa
GenBank Accession NumberNM_004988
Gene Symbol MAGEA1
Gene ID (NCBI) 4100
RRIDAB_10859942
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP43355
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MAGEA1, also named as CT1.1, MZ2-E, MAGE1 and MAGE1A, is the first gene reported to encode a CTL-defined human tumor antigen. It may play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. MAGEA1 provided direct evidence for the power of the cDNA expression library as an effective strategy to identify genes encoding tumor antigens recognized by HLA-restricted T cells.(PMID:16951217 ) The antibody is specific to MAGEA1.