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MAML3 Polyclonal antibody, PBS Only

MAML3 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 23263-1-PBS

Print datasheet

Synonyms

验证数据展示

  • WB analysis of HEK-293 using 23263-1-AP (same clone as 23263-1-PBS)

    WB analysis of HEK-293 using 23263-1-AP (same clone as 23263-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 23263-1-AP (MAML3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23263-1-PBS in a different storage buffer formulation.

  • IF Staining of HEK-293 using 23263-1-AP (same clone as 23263-1-PBS)

    IF Staining of HEK-293 using 23263-1-AP (same clone as 23263-1-PBS)

    Immunofluorescent analysis of HEK-293 cells using 23263-1-AP (MAML3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 23263-1-PBS in a different storage buffer formulation.

产品信息

23263-1-PBS targets MAML3 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen MAML3 fusion protein Ag19788 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name mastermind-like 3 (Drosophila)
Synonyms
Calculated Molecular Weight 1133 aa, 122 kDa
Observed Molecular Weight 122 kDa
GenBank Accession NumberBC137131
Gene Symbol MAML3
Gene ID (NCBI) 55534
RRIDAB_2879242
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96JK9
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The three MAML genes are widely expressed in adult tissues but exhibit distinct expression patterns in mouse early spinal cord development. All MAML proteins localize to nuclear bodies, share a conserved basic domain in their N termini that binds to the ankyrin repeat domain of Notch, and contain a transcriptional activation domain in their C termini. MAML3 acts as a transcriptional coactivator for NOTCH proteins and has been shown to amplify NOTCH-induced transcription of HES1.