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验证数据展示

  • IHC staining of rat brain using 67423-1-Ig (same clone as 67423-1-PBS)

    IHC staining of rat brain using 67423-1-Ig (same clone as 67423-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 67423-1-Ig (MAP1B antibody) at dilution of 1:5000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67423-1-PBS in a different storage buffer formulation.

  • IF Staining of rat brain using 67423-1-Ig (same clone as 67423-1-PBS)

    IF Staining of rat brain using 67423-1-Ig (same clone as 67423-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed rat brain tissue using 67423-1-Ig (MAP1B antibody), at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67423-1-PBS in a different storage buffer formulation.

  • IHC staining of rat brain using 67423-1-Ig (same clone as 67423-1-PBS)

    IHC staining of rat brain using 67423-1-Ig (same clone as 67423-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 67423-1-Ig (MAP1B antibody) at dilution of 1:5000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67423-1-PBS in a different storage buffer formulation.

MAP1B Monoclonal antibody, PBS Only

MAP1B Monoclonal Antibody for IHC, IF-P, ELISA
Cat No. 67423-1-PBS

产品说明书

CloneNo. 1E6B9

宿主/亚型

Mouse / IgG1

种属反应性

Human, rat, mouse

应用

IHC, IF-P, ELISA

别名

DKFZp686E1099, DKFZp686F1345, FLJ38954, FUTSCH, MAP 1B, MAP1B, MAP5

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67423-1-PBS targets MAP1B in IHC, IF-P, ELISA applications and shows reactivity with Human, rat, mouse samples.

经测试应用 IHC, IF-P, ELISA Application Description
经测试反应性 Human, rat, mouse
免疫原 MAP1B fusion protein Ag17709 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 microtubule-associated protein 1B
别名 DKFZp686E1099, DKFZp686F1345, FLJ38954, FUTSCH, MAP 1B, MAP1B, MAP5
计算分子量 2468 aa, 271 kDa
GenBank蛋白编号BC141853
基因名称 MAP1B
Gene ID (NCBI) 4131
RRIDAB_2918490
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP46821
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Microtubule-associated protein 1B (MAP1B) is a cytoskeleton protein which can promote microtubule assembly. Previous reports have suggested that this protein is closely involved in neuronal development based on its extensive expression in the developing brain and moderate in mature neurons. Gene disruption or knockout studies of the MAP1B gene led to a delayed development of the nervous system in mice. It includes the N-terminal heavy chain and a C-terminal light chain. The MAP1B heavy chain has a microtubule-stabilization effect, and contains an actin-binding site that may play a role in the crosslinking of actin and microtubules, a function that may be important in neurite elongation. Various isoforms around 300-350 kDa of MAP1B can be observed due to the differences in phosphorylation state. (10704485)