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TAB2 Recombinant antibody

TAB2 Uni-rAbTM Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

230118F1

Cat no : 82948-5-RR

Print datasheet

Synonyms

MAP3K7IP2, TAB-2, TAB 2, Mitogen-activated protein kinase kinase kinase 7-interacting protein 2, KIAA0733

验证数据展示

  • WB analysis using 82948-5-RR

    WB analysis using 82948-5-RR

    Various lysates were subjected to SDS PAGE followed by western blot with 82948-5-RR (MAP3K7IP2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

  • Affinity and Kinetic Characterization of 82948-5-RR

    Affinity and Kinetic Characterization of 82948-5-RR

    Biolayer interferometry (BLl) kinetic assays of 82948-5-RR against Human TAB2 were performed. The affinity constant is 65.2 pM.

经过测试的应用

Positive WB detected inHepG2 cells, HEK-293T cells, L02 cells, Raji cells, RAW 264.7 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:10000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

82948-5-RR targets TAB2 in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse
Immunogen TAB2 fusion protein Ag5742 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name mitogen-activated protein kinase kinase kinase 7 interacting protein 2
Synonyms MAP3K7IP2, TAB-2, TAB 2, Mitogen-activated protein kinase kinase kinase 7-interacting protein 2, KIAA0733
Calculated Molecular Weight 76 kDa
Observed Molecular Weight77 kDa
GenBank Accession NumberBC035910
Gene Symbol MAP3K7IP2
Gene ID (NCBI) 23118
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9NYJ8
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Tab2 has a role in the inflammatory signal transduction pathway and is involved in the reversal of NCoR-dependent and NFkB- or APP-mediated gene repression and androgen antagonist response. Besides, it is identified as a cofactor for ERBB4 to assemble NCoR corepressor complex in response to neuregulin [PMID:16469706]. It also functions as an adaptor that links TAK1 and TRAF6 in response to interleukin-1β (IL-1β) or tumour necrosis factor-α (TNF-α), and thereby mediates TAK1 activation [PMID:11460167].

实验方案

Product Specific Protocols
WB protocol for TAB2 antibody 82948-5-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols