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TAB2 Recombinant antibody, PBS Only

TAB2 Uni-rAbTM Recombinant Antibody for Indirect ELISA, WB

Host / Isotype

Rabbit / IgG

Reactivity

mouse, human

Applications

Indirect ELISA, WB

Conjugate

Unconjugated

CloneNo.

230118F1

Cat no : 82948-5-PBS

Print datasheet

Synonyms

MAP3K7IP2, TAB-2, TAB 2, Mitogen-activated protein kinase kinase kinase 7-interacting protein 2, KIAA0733

验证数据展示

  • WB analysis using 82948-5-RR (same clone as 82948-5-PBS)

    WB analysis using 82948-5-RR (same clone as 82948-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82948-5-RR (MAP3K7IP2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82948-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82948-5-RR

    Affinity and Kinetic Characterization of 82948-5-RR

    Biolayer interferometry (BLl) kinetic assays of 82948-5-RR against Human TAB2 were performed. The affinity constant is 65.2 pM.

产品信息

82948-5-PBS targets TAB2 in Indirect ELISA, WB applications and shows reactivity with mouse, human samples.

Tested Applications Indirect ELISA, WB Application Description
Tested Reactivity mouse, human
Immunogen TAB2 fusion protein Ag5742 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name mitogen-activated protein kinase kinase kinase 7 interacting protein 2
Synonyms MAP3K7IP2, TAB-2, TAB 2, Mitogen-activated protein kinase kinase kinase 7-interacting protein 2, KIAA0733
Calculated Molecular Weight 76 kDa
Observed Molecular Weight77 kDa
GenBank Accession NumberBC035910
Gene Symbol MAP3K7IP2
Gene ID (NCBI) 23118
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9NYJ8
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Tab2 has a role in the inflammatory signal transduction pathway and is involved in the reversal of NCoR-dependent and NFkB- or APP-mediated gene repression and androgen antagonist response. Besides, it is identified as a cofactor for ERBB4 to assemble NCoR corepressor complex in response to neuregulin [PMID:16469706]. It also functions as an adaptor that links TAK1 and TRAF6 in response to interleukin-1β (IL-1β) or tumour necrosis factor-α (TNF-α), and thereby mediates TAK1 activation [PMID:11460167].