验证数据展示
产品信息
82948-5-PBS targets TAB2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | TAB2 fusion protein Ag5742 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | mitogen-activated protein kinase kinase kinase 7 interacting protein 2 |
别名 | MAP3K7IP2, TAB-2, TAB 2, Mitogen-activated protein kinase kinase kinase 7-interacting protein 2, KIAA0733 |
计算分子量 | 76 kDa |
观测分子量 | 77 kDa |
GenBank蛋白编号 | BC035910 |
基因名称 | MAP3K7IP2 |
Gene ID (NCBI) | 23118 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q9NYJ8 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Tab2 has a role in the inflammatory signal transduction pathway and is involved in the reversal of NCoR-dependent and NFkB- or APP-mediated gene repression and androgen antagonist response. Besides, it is identified as a cofactor for ERBB4 to assemble NCoR corepressor complex in response to neuregulin [PMID:16469706]. It also functions as an adaptor that links TAK1 and TRAF6 in response to interleukin-1β (IL-1β) or tumour necrosis factor-α (TNF-α), and thereby mediates TAK1 activation [PMID:11460167].