MCM4 Monoclonal antibody, PBS Only
MCM4 Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
Human, mouse, rat
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2H2A1
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy MCM4 Ready-To-Use IHC Kit. MCM4 primary antibody included.
产品信息
67103-1-PBS targets MCM4 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
| Tested Applications | WB, Indirect ELISA Application Description |
| Tested Reactivity | Human, mouse, rat |
| Immunogen | MCM4 fusion protein Ag28642 种属同源性预测 |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | minichromosome maintenance complex component 4 |
| Synonyms | CDC21, CDC21 homolog, CDC54, hCdc21, MCM4, P1 CDC21 |
| Calculated Molecular Weight | 863 aa, 97 kDa |
| Observed Molecular Weight | 97 kDa |
| GenBank Accession Number | BC031061 |
| Gene Symbol | MCM4 |
| Gene ID (NCBI) | 4173 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P33991 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
DNA replication licensing factor MCM4 (MCM4), also named Cdc21, acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of
two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box
of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
