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验证数据展示

  • FC experiment of THP-1 using 98044-1-RR (same clone as 98044-1-PBS)

    FC experiment of THP-1 using 98044-1-RR (same clone as 98044-1-PBS)

    1x10^6 untreated or PMA, LPS and Brefeldin A treated THP-1 cells were intracellularly stained with 0.5 ug Anti-Human MCP-1 Rabbit Recombinant Antibody (98044-1-RR, Clone: 230270A7) and PE-conjugated Goat Anti-Rabbit IgG. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98044-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98044-1-RR

    Affinity and Kinetic Characterization of 98044-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98044-1-RR against Human MCP-1/CCL2 were performed. The affinity constant is 8.71 nM.

Anti-Human MCP-1/CCL2 Rabbit Recombinant Antibody, PBS Only

MCP-1/CCL2 Uni-rAbTM Recombinant Antibody for FC (Intra)
Cat No. 98044-1-PBS

产品说明书

CloneNo. 230270A7

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC (Intra)

别名

CCL2, MCP1, MCP-1, CCL-2, CCL 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98044-1-PBS targets MCP-1/CCL2 in FC (Intra) applications and shows reactivity with human samples.

经测试应用 FC (Intra) Application Description
经测试反应性 human
免疫原 Fusion Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 chemokine (C-C motif) ligand 2
别名 CCL2, MCP1, MCP-1, CCL-2, CCL 2
计算分子量 99 aa, 11 kDa
GenBank蛋白编号BC009716
基因名称 MCP-1/CCL2
Gene ID (NCBI) 6347
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP13500
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Monocyte chemotactic protein 1 (MCP-1; also known as CCL2), is chemotactic for monocyte/macrophage, B-cell, and T-lymphocyte, and belongs to the CC subfamily of chemokines. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis.