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Anti-Human MCP-1/CCL2 Rabbit Recombinant Antibody, PBS Only

MCP-1/CCL2 Uni-rAbTM Recombinant Antibody for FC (Intra)

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC (Intra)

Conjugate

Unconjugated

CloneNo.

230270A7

Cat no : 98044-1-PBS

Print datasheet

Synonyms

CCL2, MCP1, MCP-1, CCL-2, CCL 2

验证数据展示

  • FC experiment of THP-1 using 98044-1-RR (same clone as 98044-1-PBS)

    FC experiment of THP-1 using 98044-1-RR (same clone as 98044-1-PBS)

    1x10^6 untreated or PMA, LPS and Brefeldin A treated THP-1 cells were intracellularly stained with 0.5 ug Anti-Human MCP-1 Rabbit Recombinant Antibody (98044-1-RR, Clone: 230270A7) and PE-conjugated Goat Anti-Rabbit IgG. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98044-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98044-1-RR

    Affinity and Kinetic Characterization of 98044-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98044-1-RR against Human MCP-1/CCL2 were performed. The affinity constant is 8.71 nM.

产品信息

98044-1-PBS targets MCP-1/CCL2 in FC (Intra) applications and shows reactivity with human samples.

Tested Applications FC (Intra) Application Description
Tested Reactivity human
Immunogen Fusion Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name chemokine (C-C motif) ligand 2
Synonyms CCL2, MCP1, MCP-1, CCL-2, CCL 2
Calculated Molecular Weight 99 aa, 11 kDa
GenBank Accession NumberBC009716
Gene Symbol MCP-1/CCL2
Gene ID (NCBI) 6347
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP13500
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Monocyte chemotactic protein 1 (MCP-1; also known as CCL2), is chemotactic for monocyte/macrophage, B-cell, and T-lymphocyte, and belongs to the CC subfamily of chemokines. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis.