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验证数据展示

  • IF Staining of HeLa using CL488-20139

    IF Staining of HeLa using CL488-20139

    Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using CoraLite® Plus 488 MCT1 antibody (CL488-20139) at dilution of 1:200.

  • Featured Product
  • KD/KO验证

CoraLite® Plus 488-conjugated MCT1 Polyclonal antibody

MCT1 Polyclonal Antibody for IF/ICC
Cat No. CL488-20139

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IF/ICC

别名

FLJ36745, HHF7, MCT, MCT 1, MCT1, Monocarboxylate transporter 1, SLC16A1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格: 

-/ -

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经过测试的应用

Positive IF/ICC detected inHeLa cells
Planning an IHC experiment? We recommend our IHCeasy SLC16A1/MCT1 Ready-To-Use IHC Kit. SLC16A1/MCT1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 20139-1-AP

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-20139 targets MCT1 in IF/ICC applications and shows reactivity with human, mouse samples.

经测试应用 IF/ICC Application Description
经测试反应性 human, mouse
免疫原 MCT1 fusion protein Ag14098 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
别名 FLJ36745, HHF7, MCT, MCT 1, MCT1, Monocarboxylate transporter 1, SLC16A1
计算分子量 500 aa, 54 kDa
观测分子量 38-45 kDa
GenBank蛋白编号BC026317
基因名称 MCT1
Gene ID (NCBI) 6566
RRIDAB_3084029
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP53985
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

MCT1, the SLC16A1 gene product, is a trans-membrane symporter involved in lactate and pyruvate transportation. It plays an important role in lactic acid transport and H+ clearance in cancer cells. MCT overexpression had been observed in various cancers and may play an important role in tumorigenesis. Two isoforms of MCT1 exist due to the alternative splicing, with predicted MW of 54 kDa and 46 kDa, respectively. While western blot analysis detected MCT1 at an apparent molecular mass of 40-50 kDa.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 MCT1 antibody CL488-20139Download protocol
Standard Protocols
Click here to view our Standard Protocols