验证数据展示
产品信息
84797-4-PBS targets MCT4 in WB, IF-P, Indirect ELISA applications and shows reactivity with human samples.
Tested Applications | WB, IF-P, Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | MCT4 fusion protein Ag18788 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | solute carrier family 16, member 3 (monocarboxylic acid transporter 4) |
Synonyms | SLC16A3, MCT-4, MCT3, MCT 4, 242296E3 |
Calculated Molecular Weight | 465 aa, 49 kDa |
Observed Molecular Weight | 38-42 kDa |
GenBank Accession Number | BC112269 |
Gene Symbol | MCT4 |
Gene ID (NCBI) | 9123 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | O15427 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The monocarboxylate transporter 4 (MCT4, also known as SLC16A3) is involved in the transportation of metabolically important monocarboxylates such as lactate, pyruvate, acetate and ketone bodies. It is widely expressed, particularly strongly in glycolytic tissues such as white skeletal muscle fibres, astrocytes, white blood cells, chondrocytes and some mammalian cell lines. MCT4 is also linked to tumor biology because it mediates lactate transport across membranes resulting in antiapoptotic effects.