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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84797-4-RR (same clone as 84797-4-PBS)

    WB analysis using 84797-4-RR (same clone as 84797-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84797-4-RR (MCT4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84797-4-PBS in a different storage buffer formulation.

  • IF Staining of mouse skeletal muscle using 84797-4-RR (same clone as 84797-4-PBS)

    IF Staining of mouse skeletal muscle using 84797-4-RR (same clone as 84797-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse skeletal muscle tissue using MCT4 antibody (84797-4-RR, Clone: 242296E3 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84797-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84797-4-RR

    Affinity and Kinetic Characterization of 84797-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84797-4-RR against Human MCT4 were performed. The affinity constant is 3.02 nM.

MCT4 Recombinant antibody, PBS Only

MCT4 Uni-rAbTM Recombinant Antibody for WB, IF-P, Indirect ELISA
Cat No. 84797-4-PBS

产品说明书

CloneNo. 242296E3

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IF-P, Indirect ELISA

别名

SLC16A3, MCT-4, MCT3, MCT 4, 242296E3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy MCT4 Ready-To-Use IHC Kit. MCT4 primary antibody included.

产品信息

84797-4-PBS targets MCT4 in WB, IF-P, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF-P, Indirect ELISA Application Description
经测试反应性 human
免疫原 MCT4 fusion protein Ag18788 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
别名 SLC16A3, MCT-4, MCT3, MCT 4, 242296E3
计算分子量 465 aa, 49 kDa
观测分子量 38-42 kDa
GenBank蛋白编号BC112269
基因名称 MCT4
Gene ID (NCBI) 9123
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDO15427
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The monocarboxylate transporter 4 (MCT4, also known as SLC16A3) is involved in the transportation of metabolically important monocarboxylates such as lactate, pyruvate, acetate and ketone bodies. It is widely expressed, particularly strongly in glycolytic tissues such as white skeletal muscle fibres, astrocytes, white blood cells, chondrocytes and some mammalian cell lines. MCT4 is also linked to tumor biology because it mediates lactate transport across membranes resulting in antiapoptotic effects.