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  • Featured Product
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MEPE Polyclonal antibody, PBS Only

MEPE Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 18804-1-PBS

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Synonyms

验证数据展示

  • WB analysis of HepG2 using 18804-1-AP (same clone as 18804-1-PBS)

    WB analysis of HepG2 using 18804-1-AP (same clone as 18804-1-PBS)

    HepG2 cells were subjected to SDS PAGE followed by western blot with 18804-1-AP (MEPE antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18804-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 18804-1-AP (same clone as 18804-1-PBS)

    WB analysis of HeLa using 18804-1-AP (same clone as 18804-1-PBS)

    WB result of MEPE antibody (18804-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-MEPE transfected HeLa cells. This data was developed using the same antibody clone with 18804-1-PBS in a different storage buffer formulation.

产品信息

18804-1-PBS targets MEPE in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name matrix extracellular phosphoglycoprotein
Synonyms
Calculated Molecular Weight 525 aa, 58 kDa
Observed Molecular Weight 43 kDa, 98 kDa
GenBank Accession NumberBC128158
Gene Symbol MEPE
Gene ID (NCBI) 56955
RRIDAB_2143574
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9NQ76
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Matrix extracellular phosphoglycoprotein (MEPE), also known as osteoblast/osteocyte factor 45 (OF45), is amember of the small integrin-binding ligand N-linked glycopro-tein (SIBLING) family (PMID: 12952171). MEPE promotes renal phosphate excretion and modulates mineralization (PMID: 22582013). It can be phosphorylated by secreted protein kinases (PMID: 14962809). MEPE is expressed in osteoblasts, osteocytes and odontoblasts, and the expression has also been reported in numerous human tumor cell lines (PMID: 14962809; 20145617). It is a 525-amino acid protein with a calculated molecular weight of 58 kDa. This antibody raised against a synthetic peptide (CTHGRKYHYVPHRQNNSTR) detects a major band (43 kDa) and two minor bands (98 kDa and 34 kDa).