MZB1 Polyclonal antibody

MZB1 Polyclonal Antibody for WB, IHC, ELISA
Cat No. 11454-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, ELISA and More (1)

hypothetical protein MGC29506, MZB1, PACAP, pERp1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inRaji cells
Positive IHC detected inhuman gliomas tissue, human small intestine tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Planning an IHC experiment? We recommend our IHCeasy MZB1 Ready-To-Use IHC Kit. MZB1 primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

11454-1-AP targets MZB1 in WB, IF, IHC, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, ELISA Application Description
文献引用应用WB, IF, IHC
经测试反应性 human
文献引用反应性human
免疫原 MZB1 fusion protein Ag2015 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 hypothetical protein MGC29506
别名 hypothetical protein MGC29506, MZB1, PACAP, pERp1
计算分子量 189 aa, 21 kDa
观测分子量 19-21 kDa
GenBank蛋白编号BC021275
基因名称 MZB1
Gene ID (NCBI) 51237
RRIDAB_832820
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8WU39
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

MZB1, also named as ,PACAP, MGC29506 and pERp1, belongs to the PERP1 family. It is associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. MGC29506(PACAP) may exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity. Isoform 2 may be involved in regulation of apoptosis. (PubMed: 11350957) MZB1 has 5 isoforms with MW 21kd and 7-13kd.

实验方案

Product Specific Protocols
WB protocol for MZB1 antibody 11454-1-APDownload protocol
IHC protocol for MZB1 antibody 11454-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIHC

Clin Cancer Res

Integrative array-based approach identifies MZB1 as a frequently methylated putative tumor suppressor in hepatocellular carcinoma.

Authors - Matsumura Satoshi S
humanIHC,IF

J Pathol

Proteomic profiling identifies novel diagnostic biomarkers and molecular subtypes for mucinous tubular and spindle cell carcinoma of the kidney.

Authors - Huiya Xu
humanIHC

Int J Cancer

Epigenetic suppression of the immunoregulator MZB1 is associated with the malignant phenotype of gastric cancer.

Authors - Mitsuro Kanda
humanWB

J Biol Chem

Transgenic expression of microRNA-185 causes a developmental arrest of T cells by targeting multiple genes including Mzb1.

Authors - Belkaya Serkan S
humanWB,IHC,IF

Arthritis Res Ther

Increase of MZB1 in B cells in systemic lupus erythematosus: proteomic analysis of biopsied lymph nodes.

Authors - Aya Miyagawa-Hayashino
humanIHC

Oncol Lett

MZB1 expression indicates poor prognosis in estrogen receptor-positive breast cancer.

Authors - Manabu Watanabe
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