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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 13256-1-AP (same clone as 13256-1-PBS)

    WB analysis using 13256-1-AP (same clone as 13256-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13256-1-AP (MLXIPL antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13256-1-PBS in a different storage buffer formulation.

  • IP experiment of HepG2 using 13256-1-AP (same clone as 13256-1-PBS)

    IP experiment of HepG2 using 13256-1-AP (same clone as 13256-1-PBS)

    IP result of anti-MLXIPL (IP:13256-1-AP, 4ug; Detection:13256-1-AP 1:1000) with HepG2 cells lysate 3600ug. This data was developed using the same antibody clone with 13256-1-PBS in a different storage buffer formulation.

MLXIPL Polyclonal antibody, PBS Only

MLXIPL Polyclonal Antibody for WB, IP, Indirect ELISA
Cat No. 13256-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IP, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

13256-1-PBS targets MLXIPL in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 MLXIPL fusion protein Ag3481 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 MLX interacting protein-like
别名
计算分子量 852 aa, 93 kDa
观测分子量 65 kDa
GenBank蛋白编号BC012925
基因名称 MLXIPL
Gene ID (NCBI) 51085
RRIDAB_2266665
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9NP71
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Carbohydrate response element-binding protein (ChREBP), also known as MLXIPL, is a glucose-responsive transcription factor that has a fundamental role in the glucose-mediated induction of genes involved in hepatic glycolysis and lipogenesis. Circulating blood glucose levels affect ChREBP activity in hepatocytes largely by post-translational mechanisms that include phosphorylation-dependent subcellular localization [PMID:21665952]. It enhances expression of the liver pyruvate kinase (LPK) gene and all lipogenic enzyme genes resulting in the conversion of excess dietary carbohydrate into triglycerides that can be stored as fat [PMID:15118080]. Molecular Weight of ChREBP splice variants: 62/78/91/93 kDa.