验证数据展示
产品信息
30615-1-PBS targets MMP11 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | MMP11 fusion protein Ag31191 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | matrix metallopeptidase 11 (stromelysin 3) |
别名 | |
计算分子量 | 55 kDa |
观测分子量 | 50-55 kDa |
GenBank蛋白编号 | NM_005940 |
基因名称 | MMP11 |
Gene ID (NCBI) | 4320 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P24347 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Matrix metalloproteinase 11 (MMP11), also named stromelysin-3, is a member of the stromelysin subgroup belonging to MMPs superfamily. The role of MMP11 in cancer progression has been shown by several preclinical observations: its expression promotes tumor take in mice, homing of malignant epithelial cells, cancer progression by remodeling extracellular matrix, and antiapoptotic and antinecrotic effect on tumor cells (PMID: 19509157, 26892540). MMP11 has a calculated molecular mass of 55 kDa.