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MS4A2 Polyclonal antibody

MS4A2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 26808-1-AP

Print datasheet

Synonyms

APY, ATOPY, FCER1B, FCERI, IgE Fc receptor subunit beta, IGEL, IGER, IGHER, MS4A1, MS4A2

验证数据展示

  • WB analysis using 26808-1-AP

    WB analysis using 26808-1-AP

    mouse lung tissue lysates were subjected to SDS PAGE followed by western blot with 26808-1-AP (MS4A2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inmouse lung tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

26808-1-AP targets MS4A2 in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse
Immunogen MS4A2 fusion protein Ag25196 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)
Synonyms APY, ATOPY, FCER1B, FCERI, IgE Fc receptor subunit beta, IGEL, IGER, IGHER, MS4A1, MS4A2
Calculated Molecular Weight 244 aa, 27 kDa
Observed Molecular Weight 25-27 kDa
GenBank Accession NumberBC074843
Gene Symbol MS4A2
Gene ID (NCBI) 2206
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ01362
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

MS4A is a new gene family with four transmembrane-spanning domains and is crucial for cell differentiation, signaling, and cell cycle control. The membrane-spanning 4 domains, superfamily A, number 2 gene (MS4A2, also named as the beta-chain of the high affinity IgE receptor or FcεRIβ gene, FCER1B), as a member of the MS4A family, is a component of the high-affinity IgE receptor, with co-immunoprecipitation experiments demonstrating that it associates with FcɛRIα and FcRγ to form a tetrameric receptor complex (αβγ2) that is expressed on mast cells and basophils at high density(PMID: 25835430). MS4A2 is strongly associated with the prognosis of lung adenocarcinoma and lung cancer brain metastases(PMID: 37533433).

实验方案

Product Specific Protocols
WB protocol for MS4A2 antibody 26808-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols