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MSH2 Recombinant antibody, PBS Only

MSH2 Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

6O4

Cat No : 82775-1-PBS

Print datasheet

Synonyms

COCA1, FCC1, hMSH2, HNPCC, HNPCC1, LCFS2, MSH2, MutS protein homolog 2

验证数据展示

  • WB analysis using 82775-1-RR (same clone as 82775-1-PBS)

    WB analysis using 82775-1-RR (same clone as 82775-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82775-1-RR (MSH2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82775-1-PBS in a different storage buffer formulation.

  • Affinity experiments of 82775-1-RR

    Affinity experiments of 82775-1-RR

    Biolayer interferometry (BLl) kinetic assays of 82775-1-RR against Human MSH2 were performed. The affinity constant is below 1 pM.

产品信息

82775-1-PBS targets MSH2 in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen MSH2 fusion protein Ag7835 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
Synonyms COCA1, FCC1, hMSH2, HNPCC, HNPCC1, LCFS2, MSH2, MutS protein homolog 2
Calculated Molecular Weight 105 kDa
Observed Molecular Weight 100 kDa-105 kDa
GenBank Accession NumberBC021566
Gene Symbol MSH2
Gene ID (NCBI) 4436
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP43246
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

MSH2, named for its homologous to the E.coli MutS gene, takes part in DNA mismatch repair(MMR) to maintain the stability of DNA. MSH2 contains a helix-turn-helix domain, which responds for binding to DNA. Also, MSH2 has a direct role in mutation avoidance and micro-satellite stability in cell.