验证数据展示
产品信息
82775-1-PBS targets MSH2 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | MSH2 fusion protein Ag7835 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) |
别名 | MSH 2, 6O4 |
计算分子量 | 105 kDa |
观测分子量 | 100 kDa-105 kDa |
GenBank蛋白编号 | BC021566 |
基因名称 | MSH2 |
Gene ID (NCBI) | 4436 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P43246 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
MSH2, named for its homologous to the E.coli MutS gene, takes part in DNA mismatch repair(MMR) to maintain the stability of DNA. MSH2 contains a helix-turn-helix domain, which responds for binding to DNA. Also, MSH2 has a direct role in mutation avoidance and micro-satellite stability in cell.