验证数据展示
产品信息
25780-1-PBS targets MTCL1 in WB, Indirect ELISA applications and shows reactivity with human, canine samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, canine |
| 免疫原 | MTCL1 fusion protein Ag22718 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | KIAA0802 |
| 别名 | |
| 计算分子量 | 1905 aa, 209 kDa |
| 观测分子量 | 250 kDa |
| GenBank蛋白编号 | BC040542 |
| 基因名称 | MTCL1 |
| Gene ID (NCBI) | 23255 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9Y4B5 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Microtubule cross‐linking factor 1 (MTCL1) is a MT‐regulating protein that plays essential roles in accumulating the non-centrosomal MTs into the apicobasal MT bundles. MTCL1, identified as a binding protein of the cell polarity‐regulating kinase, PAR‐1b/MARK2, is recruited to the Golgi membranes through interactions with CLASPs and AKAP450/CG-NAP, and promotes microtubule growth from the Golgi membrane. Western blot analysis detected MTCL1 at an apparent molecular mass of 250 kDa as indicated in the literature (PMID: 23902687, 28283581).