验证数据展示
产品信息
68713-1-PBS targets MTF2 in WB, Indirect ELISA applications and shows reactivity with Human, Rat, Rabbit, Mouse samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | Human, Rat, Rabbit, Mouse |
| 免疫原 | MTF2 fusion protein Ag9384 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | metal response element binding transcription factor 2 |
| 别名 | dJ976O13.2, hPCl2, M96, MTF2, PCL2, Polycomb like protein 2, RP5 976O13.1 |
| 计算分子量 | 536 aa, 61 kDa |
| 观测分子量 | 55 kDa, 60 kDa, 75 kDa |
| GenBank蛋白编号 | BC010013 |
| 基因名称 | MTF2 |
| Gene ID (NCBI) | 22823 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9Y483 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
MTF2, also named as Metal-response element-binding transcription factor 2, is a 593 amino acid protein. It exists several isoforms and the range of the molecular weight of isoforms are about 55-60 kDa and 29 kDa. MTF2 contains 2 PHD-type zinc fingers and belongs to the Polycomblike family. MTF2 acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex, leading to enhance PRC2 H3K27me3 methylation activity and regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation.