验证数据展示
产品信息
68713-1-PBS targets MTF2 in WB, Indirect ELISA applications and shows reactivity with Human, Rat, Rabbit, Mouse samples.
| Tested Applications | WB, Indirect ELISA Application Description |
| Tested Reactivity | Human, Rat, Rabbit, Mouse |
| Immunogen | MTF2 fusion protein Ag9384 种属同源性预测 |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | metal response element binding transcription factor 2 |
| Synonyms | dJ976O13.2, hPCl2, M96, MTF2, PCL2, Polycomb like protein 2, RP5 976O13.1 |
| Calculated Molecular Weight | 536 aa, 61 kDa |
| Observed Molecular Weight | 55 kDa, 60 kDa, 75 kDa |
| GenBank Accession Number | BC010013 |
| Gene Symbol | MTF2 |
| Gene ID (NCBI) | 22823 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q9Y483 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
MTF2, also named as Metal-response element-binding transcription factor 2, is a 593 amino acid protein. It exists several isoforms and the range of the molecular weight of isoforms are about 55-60 kDa and 29 kDa. MTF2 contains 2 PHD-type zinc fingers and belongs to the Polycomblike family. MTF2 acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex, leading to enhance PRC2 H3K27me3 methylation activity and regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation.