验证数据展示
产品信息
29946-1-PBS targets MYD88 in WB, IHC, Indirect ELISA applications and shows reactivity with mouse, rat samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | mouse, rat |
免疫原 | MYD88 fusion protein Ag30662 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | myeloid differentiation primary response gene 88 |
别名 | |
计算分子量 | 34 kDa |
观测分子量 | 29-34 kDa |
GenBank蛋白编号 | NM_010851 |
基因名称 | Myd88 |
Gene ID (NCBI) | 17874 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P22366 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
MYD88 is a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. MYD88 is the key adaptor protein for the interleukin-1 receptor (IL-1R) and most Toll-like receptors (TLRs), which are essential for innate immunity and pathogen-associated molecular pattern recognition. Mutations in the MyD88 gene lead to the development of cancer in humans and mice suggesting that MyD88 also plays a cell autonomous role in tissue homeostasis. MYD88 is detected in bone marrow.