验证数据展示
经过测试的应用
Positive FC (Intra) detected in | K-562 cells |
推荐稀释比
应用 | 推荐稀释比 |
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Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-67969 targets MYD88 in FC (Intra) applications and shows reactivity with human, mouse, rat, pig, rabbit samples.
经测试应用 | FC (Intra) Application Description |
经测试反应性 | human, mouse, rat, pig, rabbit |
免疫原 | MYD88 fusion protein Ag27659 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | myeloid differentiation primary response gene (88) |
别名 | 2E10D3 |
计算分子量 | 33 kDa |
观测分子量 | 33 kDa |
GenBank蛋白编号 | BC013589 |
基因名称 | MYD88 |
Gene ID (NCBI) | 4615 |
RRID | AB_2923842 |
偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
最大激发/发射波长 | 493 nm / 522 nm |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q99836 |
储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
MYD88 is a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. MYD88 is the key adaptor protein for the interleukin-1 receptor (IL-1R) and most Toll-like receptors (TLRs), which are essential for innate immunity and pathogen-associated molecular pattern recognition. Mutations in the MyD88 gene lead to the development of cancer in humans and mice suggesting that MyD88 also plays a cell autonomous role in tissue homeostasis.
实验方案
Product Specific Protocols | |
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FC protocol for CL Plus 488 MYD88 antibody CL488-67969 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |