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验证数据展示

  • WB analysis using 84085-3-RR (same clone as 84085-3-PBS)

    WB analysis using 84085-3-RR (same clone as 84085-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84085-3-RR (MYO6 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84085-3-PBS in a different storage buffer formulation.

  • WB analysis of LNCaP using 84085-3-RR (same clone as 84085-3-PBS)

    WB analysis of LNCaP using 84085-3-RR (same clone as 84085-3-PBS)

    LNCaP cells were subjected to SDS PAGE followed by western blot with 84085-3-RR (MYO6 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84085-3-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP01001-1

    Cytometric bead array standard curve of MP01001-1

    Cytometric bead array standard curve of MP01001-1, MYO6 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84085-3-PBS. Detection antibody: 84085-1-PBS. Standard: Ag24906. Range: 0.781-100 ng/ml.

  • Cytometric bead array standard curve of MP01001-3

    Cytometric bead array standard curve of MP01001-3

    Cytometric bead array standard curve of MP01001-3, MYO6 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84085-2-PBS. Detection antibody: 84085-3-PBS. Standard: Ag24906. Range: 0.781-100 ng/ml.

MYO6 Recombinant antibody, PBS Only (Capture/Detector)

MYO6 Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA
Cat No. 84085-3-PBS

产品说明书

CloneNo. 241251G11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Cytometric bead array, Indirect ELISA

别名

Unconventional myosin 6, myosin VI, KIAA0389, DFNB37, DFNA22

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy MYO6 Ready-To-Use IHC Kit. MYO6 primary antibody included.

产品信息

84085-3-PBS targets MYO6 as part of a matched antibody pair:

MP01001-1: 84085-3-PBS capture and 84085-1-PBS detection (validated in Cytometric bead array)

MP01001-3: 84085-2-PBS capture and 84085-3-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human
免疫原 MYO6 fusion protein Ag24906 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 myosin VI
别名 Unconventional myosin 6, myosin VI, KIAA0389, DFNB37, DFNA22
计算分子量 1285 aa, 149 kDa
观测分子量 145-150 kDa
GenBank蛋白编号BC146764
基因名称 MYO6
Gene ID (NCBI) 4646
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9UM54
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

MYO6, an actin-based motor protein, is the only myosin known to move toward the minus end of actin filaments. MYO6 is highly expressed in the inner and outer hair cells of the ear, retina, and polarized epithelial cells such as kidney proximal tubule cells and intestinal enterocytes. And it participates in a wide range of biological processes within cells, including clathrin-mediated endocytosis, vesicular membrane traffic, polarized secretion, and autophagy (PMID: 23620821; PMID: 28591580). Previous studies showed that MYO6 is upregulated in various types of cancer, and it has been widely reported to contribute to tumor cell migration and metastasis. Some articles indicate that MYO6 is associated with prostate cancer, lung cancer, human colorectal cancer and gastric cancer (PMID: 29022908).