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验证数据展示

  • WB analysis using 66092-1-Ig (same clone as 66092-1-PBS)

    WB analysis using 66092-1-Ig (same clone as 66092-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66092-1-Ig (Melanophilin antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66092-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 66092-1-Ig (same clone as 66092-1-PBS)

    IHC staining of human kidney using 66092-1-Ig (same clone as 66092-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66092-1-Ig (Melanophilin antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 66092-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 66092-1-Ig (same clone as 66092-1-PBS)

    IHC staining of human kidney using 66092-1-Ig (same clone as 66092-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66092-1-Ig (Melanophilin antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 66092-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 66092-1-Ig (same clone as 66092-1-PBS)

    IF Staining of HepG2 using 66092-1-Ig (same clone as 66092-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using 66092-1-Ig (Melanophilin antibody) at dilution of 1:100 and Alexa Fluor 488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66092-1-PBS in a different storage buffer formulation.

MLPH Monoclonal antibody, PBS Only

MLPH Monoclonal Antibody for WB, IHC, IF/ICC, ELISA
Cat No. 66092-1-PBS

产品说明书

CloneNo. 1A8D12

宿主/亚型

Mouse / IgG1

种属反应性

human, pig

应用

WB, IHC, IF/ICC, ELISA

别名

SlaC2-a, SLAC2A, SLAC2 A, Melanophilin, Exophilin-3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

66092-1-PBS targets MLPH in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human, pig samples.

经测试应用 WB, IHC, IF/ICC, ELISA Application Description
经测试反应性 human, pig
免疫原 MLPH fusion protein Ag19286 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 melanophilin
别名 SlaC2-a, SLAC2A, SLAC2 A, Melanophilin, Exophilin-3
计算分子量 66 kDa
观测分子量 66 kDa
GenBank蛋白编号BC001653
基因名称 MLPH
Gene ID (NCBI) 79083
RRIDAB_11232039
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9BV36
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Melanophilin (MLPH) is a member of the exophilin subfamily of Rab effector proteins. MLPH is a modular protein, forming a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. It regulates retention of melanosomes at the peripheral actin cytoskeleton of melanocytes, a process essential for normal mammalian pigmentation. Defects in MLPH are a cause of Griscelli syndrome type 3 (GS3), which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft.