验证数据展示
产品信息
80219-1-PBS targets Mono/Di-Methyl-Histone H3 (Lys9) in WB, IF/ICC, Indirect ELISA applications and shows reactivity with rat, mouse, human samples.
Tested Applications | WB, IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | rat, mouse, human |
Immunogen | Peptide 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | histone cluster 1, H3a |
Synonyms | HIST1H3A, 1E12, Histone-H3, HistoneH3, Histone H3 |
Observed Molecular Weight | 15-18 kDa |
GenBank Accession Number | BC066245 |
Gene Symbol | HIST1H3A |
Gene ID (NCBI) | 8350 |
RRID | AB_2918878 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P68431 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Histones, including H1/H5 (linker histones), H2, H3, and H4 (core histones), are nucleic proteins which interact with DNA to form the nucleosomes and play important roles in gene regulation and DNA replication. Histone proteins are highly post-translationally modified while Histone H3 is the most extensively modified. Methylation of Histone H3 at lysine 9 is linked to transcriptional repression. This antibody is specific to monomethyl or dimethyl-Histone H3 while it does not recognize trimethyl-Histone H3 (Lys9). It is also named as H3K9me1/2.