MultiPro™ 5CFLX Anti-Human AHNAK (Polyclonal)
AHNAK Polyclonal Antibody for Single Cell (Intra)
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
Single Cell (Intra)
Conjugate
5CFLX
Barcode Sequence
CTGCGTACAGGTGGA
验证数据展示
经过测试的应用
| Positive Single Cell (Intra) detected in | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product. |
Planning an IHC experiment? We recommend our IHCeasy AHNAK Ready-To-Use IHC Kit. AHNAK primary antibody included.
推荐稀释比
| Application | Dilution |
|---|---|
| SINGLE CELL (INTRA) | <0.5ug/test |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
产品信息
G16637-1-5C targets AHNAK in Single Cell (Intra) applications and shows reactivity with Human samples.
| Tested Applications | Single Cell (Intra) Application Description |
| Tested Reactivity | Human |
| Immunogen | AHNAK fusion protein Ag9986 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Oligo Conjugate |
| Type | Polyclonal |
| Full Name | MultiPro™ 5CFLX Anti-Human AHNAK (Polyclonal) |
| Synonyms | AHNAK, AHNAK nucleoprotein, AHNAKRS, Desmoyokin, PM227 |
| Calculated Molecular Weight | 629 kDa |
| GenBank Accession Number | BC000926 |
| Gene Symbol | AHNAK |
| Gene ID (NCBI) | 79026 |
| ENSEMBL Gene ID | ENSG00000124942 |
| Conjugate | 5CFLX |
| Full Oligo Sequence | CGGAGATGTGTATAAGAGACAGCTGCGTACAGGTGGACCCATATAAGAAA |
| Barcode Sequence | CTGCGTACAGGTGGA |
| Form | Liquid |
| UNIPROT ID | Q09666 |
| Storage Buffer | PBS with 1mM EDTA and 0.09% sodium azide |
| Storage Conditions | 2-8°C Stable for one year after shipment. |
背景介绍
AHNAK, also known as desmoyokin, is described as a giant scaffold protein based on its large size (629 kDa) and ability to interact with different proteins to form multi-protein complexes. The bulk of the protein is assembled in 128-residue repetitive elements known as the central repeated
unit (CRU). Its proposed functions are quite diverse, ranging from a role in the formation of the blood brain barrier, in cell architecture and migration, to the regulation of cardiac channels and muscle membrane repair. AHNAK is differentially expressed in some cancer cell lines. The expression of AHNAK is subsequently localized to the plasma membrane of keratinocytes in human epidermis. AHNAK has been reported in many intracellular locations including the nucleus, cytoplasm and plasma membrane.
Protocols
| Our current MultiPro staining protocol for the cocktail | Download protocol |
| 10x Genomics CG000149_Demonstrated Protocol CellSurface Protein Labeling_Rev D.pdf | Download protocol |