MultiPro® 5CFLX Anti-Human AHNAK (Polyclonal)

AHNAK Polyclonal Antibody for Single Cell (Intra)

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

Single Cell (Intra)

Conjugate

5CFLX

Barcode Sequence

CTGCGTACAGGTGGA

Cat no : G16637-1-5C

Print datasheet

Synonyms

AHNAK, AHNAK nucleoprotein, AHNAKRS, Desmoyokin, PM227



经过测试的应用

Positive Single Cell (Intra) detected in10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product.
Planning an IHC experiment? We recommend our IHCeasy AHNAK Ready-To-Use IHC Kit. AHNAK primary antibody included.

推荐稀释比

ApplicationDilution
SINGLE CELL (INTRA)<0.5ug/test
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

产品信息

G16637-1-5C targets AHNAK in Single Cell (Intra) applications and shows reactivity with Human samples.

Tested Applications Single Cell (Intra) Application Description
Tested Reactivity Human
Immunogen AHNAK fusion protein Ag9986 种属同源性预测
Host / Isotype Rabbit / IgG
Class Oligo Conjugate
Type Polyclonal
Full Name MultiPro® 5CFLX Anti-Human AHNAK (Polyclonal)
Synonyms AHNAK, AHNAK nucleoprotein, AHNAKRS, Desmoyokin, PM227
Calculated Molecular Weight 629 kDa
GenBank Accession NumberBC000926
Gene Symbol AHNAK
Gene ID (NCBI) 79026
ENSEMBL Gene IDENSG00000124942
Conjugate 5CFLX
Full Oligo SequenceCGGAGATGTGTATAAGAGACAGCTGCGTACAGGTGGACCCATATAAGAAA
Barcode SequenceCTGCGTACAGGTGGA
Form Liquid
UNIPROT IDQ09666
Storage Buffer PBS with 1mM EDTA and 0.09% sodium azide
Storage Conditions2-8°C Stable for one year after shipment.

背景介绍

AHNAK, also known as desmoyokin, is described as a giant scaffold protein based on its large size (629 kDa) and ability to interact with different proteins to form multi-protein complexes. The bulk of the protein is assembled in 128-residue repetitive elements known as the central repeated unit (CRU). Its proposed functions are quite diverse, ranging from a role in the formation of the blood brain barrier, in cell architecture and migration, to the regulation of cardiac channels and muscle membrane repair. AHNAK is differentially expressed in some cancer cell lines. The expression of AHNAK is subsequently localized to the plasma membrane of keratinocytes in human epidermis. AHNAK has been reported in many intracellular locations including the nucleus, cytoplasm and plasma membrane.

Protocols

Our current MultiPro staining protocol for the cocktailDownload protocol
10x Genomics CG000149_Demonstrated Protocol CellSurface Protein Labeling_Rev D.pdfDownload protocol