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MultiPro™ 5CFLX Anti-Human Drebrin (1A12H1)

Drebrin Monoclonal Antibody for Single Cell (Intra)

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

Single Cell (Intra)

Conjugate

5CFLX

Barcode Sequence

TGTACTGAGATAGGC

CloneNo.

1A12H1

Cat no : G67589-1-5C

Print datasheet

Synonyms

D0S117E, DBN1, DKFZp434D064, Drebrin, drebrin 1

验证数据展示

  • Single Cell Sequencing experiment G67589-1-5C on Resting PBMC

    Single Cell Sequencing experiment G67589-1-5C on Resting PBMC

    G67589-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

  • Single Cell Sequencing experiment G67589-1-5C on PBMC treated with 4hr LPS + TI

    Single Cell Sequencing experiment G67589-1-5C on PBMC treated with 4hr LPS + TI

    G67589-1-5C was used to stain PBMC under 4hr LPS + TI treatment and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

经过测试的应用

Positive Single Cell (Intra) detected in10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product.
Planning an IHC experiment? We recommend our IHCeasy DBN1/Drebrin Ready-To-Use IHC Kit. DBN1/Drebrin primary antibody included.

推荐稀释比

ApplicationDilution
SINGLE CELL (INTRA)<0.5ug/test
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

产品信息

G67589-1-5C targets Drebrin in Single Cell (Intra) applications and shows reactivity with Human samples.

Tested Applications Single Cell (Intra) Application Description
Tested Reactivity Human
Immunogen Drebrin fusion protein Ag22635 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Oligo Conjugate
Type Monoclonal
Full Name MultiPro™ 5CFLX Anti-Human Drebrin (1A12H1)
Synonyms D0S117E, DBN1, DKFZp434D064, Drebrin, drebrin 1
GenBank Accession NumberBC007567
Gene Symbol Drebrin
Gene ID (NCBI) 1627
ENSEMBL Gene IDENSG00000113758
Conjugate 5CFLX
Full Oligo SequenceCGGAGATGTGTATAAGAGACAGTGTACTGAGATAGGCCCCATATAAGAAA
Barcode SequenceTGTACTGAGATAGGC
Form Liquid
UNIPROT IDQ16643
Storage Buffer PBS with 1mM EDTA and 0.09% sodium azide
Storage Conditions2-8°C Stable for one year after shipment.

背景介绍

Drebrin (DBN1) is an actin binding and stabilizing protein with roles in endocytosis, formation of dendrite spines in neurons and coordinating cell-cell synapses in immune cells. Preferentially expressed in the brain, it is highly localized in dendritic spines and regulates spine shapes. It has two isoforms that are splice variants, with drebrin A being expressed in neural cells, and drebrin E is present in several other cell types. Recently it has been reported that circulating DBN1 levels correlated with retinal nerve fiber layer defect and may reflect the severity of retinal ganglion cells injury in glaucoma patients.

Protocols

Our current MultiPro staining protocol for the cocktailDownload protocol
10x Genomics CG000149_Demonstrated Protocol CellSurface Protein Labeling_Rev D.pdfDownload protocol