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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 11410-1-AP (same clone as 11410-1-PBS)

    WB analysis using 11410-1-AP (same clone as 11410-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11410-1-AP (NAT2 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11410-1-PBS in a different storage buffer formulation.

  • IHC staining of human small intestine using 11410-1-AP (same clone as 11410-1-PBS)

    IHC staining of human small intestine using 11410-1-AP (same clone as 11410-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 11410-1-AP (NAT2 antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 11410-1-PBS in a different storage buffer formulation.

  • FC experiment of MCF-7 using 11410-1-AP (same clone as 11410-1-PBS)

    FC experiment of MCF-7 using 11410-1-AP (same clone as 11410-1-PBS)

    1x10^6 MCF-7 cells were intracellularly stained with 0.8 ug NAT2 Polyclonal antibody (11410-1-AP) and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2)(red), or 0.8 ug Rabbit IgG control Rabbit PolyAb (30000-0-AP) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 11410-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 11410-1-AP (same clone as 11410-1-PBS)

    IHC staining of human breast cancer using 11410-1-AP (same clone as 11410-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11410-1-AP (NAT2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11410-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 11410-1-AP (same clone as 11410-1-PBS)

    IHC staining of human breast cancer using 11410-1-AP (same clone as 11410-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11410-1-AP (NAT2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11410-1-PBS in a different storage buffer formulation.

NAT2 Polyclonal antibody, PBS Only

NAT2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 11410-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

11410-1-PBS targets NAT2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 NAT2 fusion protein Ag1953 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 N-acetyltransferase 2 (arylamine N-acetyltransferase)
别名
计算分子量 33.5 kDa
观测分子量38 kDa
GenBank蛋白编号BC015878
基因名称 NAT2
Gene ID (NCBI) 10
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP11245
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NAT2 (Arylamine N-acetyltransferase 2) is well-known for its role in the phase II metabolism of xenobiotics and drugs (PMID:36156098). NAT2 and its isozyme, arylamine N-acetyltransferase 1 (NAT1), play key roles in the detoxification of carcinogenic arylamines and xenobiotics by catalyzing acetyl-coenzyme A (CoA)-dependent biotransformation of arylamines to N-arylacetamides. Endogenous NAT2 expression is limited to the liver and small and large intestines, suggesting that NAT2 plays organ-specific roles (PMID:24467436).