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NCAM1/CD56 Recombinant antibody, PBS Only (Capture)

NCAM1/CD56 Uni-rAbTM Recombinant Antibody for Sandwich ELISA, Indirect ELISA, Sample test

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Sandwich ELISA, Indirect ELISA, Sample test

Conjugate

Unconjugated

CloneNo.

240078A7

Cat no : 83365-5-PBS

Print datasheet

Synonyms

CD56, NCAM1, 240078A7, NCAM 1, NCAM

验证数据展示

  • Sandwich ELISA standard curve of MP00393-4

    Sandwich ELISA standard curve of MP00393-4

    Sandwich ELISA standard curve of MP00393-4, Human NCAM1 Monoclonal Matched Antibody Pair - PBS only. 83365-5-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard Eg31816. 83365-4-PBS was HRP conjugated as the detection antibody. Range: 0.156-10 ng/mL.

  • Sample test of MP00393-4

    Sample test of MP00393-4

    The NCAM1 concentration of Human cerebrospinal fluid (CSF) samples were determined to be 127.3 ng/mL.

  • Sample test of MP00393-4

    Sample test of MP00393-4

    Serum of sixteen individual healthy human donors were measured. The NCAM1 concentration of detected samples was determined to be 1.2 ug/mL with a range of 0.7 - 1.9 ug/mL.

Planning an IHC experiment? We recommend our IHCeasy CD56/NCAM1 Ready-To-Use IHC Kit. CD56/NCAM1 primary antibody included.

产品信息

83365-5-PBS targets NCAM1/CD56 as part of a matched antibody pair:

MP00393-4: 83365-5-PBS capture and 83365-4-PBS detection (validated in Sandwich ELISA)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications Sandwich ELISA, Indirect ELISA, Sample test Application Description
Tested Reactivity human
Immunogen Fusion Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name neural cell adhesion molecule 1
Synonyms CD56, NCAM1, 240078A7, NCAM 1, NCAM
Calculated Molecular Weight 95 kDa
GenBank Accession NumberBC047244
Gene Symbol NCAM1
Gene ID (NCBI) 4684
ENSEMBL Gene IDENSG00000149294
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP13591
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Neural cell adhesion molecule 1 (NCAM1, also known as CD56) is a cell adhesion glycoprotein of the immunoglobulin (Ig) superfamily. It is a multifunction protein involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM1 is expressed on human neurons, glial cells, skeletal muscle cells, NK cells and a subset of T cells, and the expression is observed in a wide variety of human tumors, including myeloma, myeloid leukemia, neuroendocrine tumors, Wilms' tumor, neuroblastoma, and NK/T cell lymphomas. Three major isoforms of NCAM1, with molecular masses of 120, 140, and 180 kDa, are generated by alternative splicing of mRNA (PMID: 9696812). The glycosylphosphatidylinositol (GPI)-anchored NCAM120 and the transmembrane NCAM140 and NCAM180 consist of five Ig-like domains and two fibronection-type III repeats (FNIII). All three forms can be posttranslationally modified by addition of polysialic acid (PSA) (PMID: 14976519). Several other isofroms have also been described (PMID: 1856291).