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NDEL1 Monoclonal antibody, PBS Only

NDEL1 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human, mouse, rat, pig

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

1B3E9

Cat no : 68954-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 68954-1-Ig (same clone as 68954-1-PBS)

    WB analysis using 68954-1-Ig (same clone as 68954-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68954-1-Ig (NDEL1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68954-1-PBS in a different storage buffer formulation.

产品信息

68954-1-PBS targets NDEL1 in WB, ELISA applications and shows reactivity with human, mouse, rat, pig samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse, rat, pig
Immunogen NDEL1 fusion protein Ag11197 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name nudE nuclear distribution gene E homolog (A. nidulans)-like 1
Synonyms
Calculated Molecular Weight 345 aa, 38 kDa, 41 kDa
Observed Molecular Weight 38-42 kDa
GenBank Accession NumberBC026101
Gene Symbol NDEL1
Gene ID (NCBI) 81565
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9GZM8
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Nuclear distribution factor E-homolog 1 (NDE1), NDE-like 1 (NDEL1), and Lissencephaly 1 (LIS1) together involve in essential neurodevelopmental processes, including neuronal precursor proliferation and differentiation, neurite outgrowth, and neuronal migration. All three bind directly to Disrupted in Schizophrenia 1 (DISC1), a scaffold protein critical to neuronal proliferation, integration, migration, and synaptic function within the developing and adult brain.[PMID: 18469341] Nuclear distribution element-like 1 (NDEL1) was firstly identified as a regulator of the cytoskeleton in microtubule and intermediate fliament dynamics and microtubule-based transport [PMID:21948775]. It is required for organization of the cellular microtubule array and microtubule anchoring at the centrosome, which is in part by targeting the microtubule severing protein KATNA1 to the centrosome[PMID:15728732].