验证数据展示
经过测试的应用
Positive IF/ICC detected in | HeLa cells |
推荐稀释比
应用 | 推荐稀释比 |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL555-26902 targets NDRG1 in IF/ICC applications and shows reactivity with human samples.
经测试应用 | IF/ICC Application Description |
经测试反应性 | human |
免疫原 | NDRG1 fusion protein Ag25424 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | N-myc downstream regulated 1 |
别名 | CAP43, CMT4D, DRG 1, DRG1, GC4, HMSNL, N myc downstream regulated 1, NDR1, NDRG1, Protein NDRG1, PROXY1, RIT42, RTP, TARG1, TDD5 |
计算分子量 | 43 kDa |
观测分子量 | 43 kDa |
GenBank蛋白编号 | BC006260 |
基因名称 | NDRG1 |
Gene ID (NCBI) | 10397 |
RRID | AB_2919646 |
偶联类型 | CoraLite®555 Fluorescent Dye |
最大激发/发射波长 | 557 nm / 570nm |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q92597 |
储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
NDRG1 is a member of the N-myc down-regulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a highly conserved cytoplasmic protein involved in cell growth arrest and proliferation, cell differentiation, DNA damage response, heavy metal response, the hypoxia response, tumorigenesis, and metastasis. NDRG1 is a potent metastasis suppressor in multiple tumor-types. NDRG1 appears to serve as a putative tumor suppressor and is down-regulated in colorectal, gastric, cervical, ovarian and prostate cancers.
实验方案
Product Specific Protocols | |
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IF protocol for CL555 NDRG1 antibody CL555-26902 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |