验证数据展示
产品信息
66202-1-PBS targets NINJ2 in IHC, IF-P, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | IHC, IF-P, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | NINJ2 fusion protein Ag5343 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | ninjurin 2 |
别名 | Nerve injury induced protein 2, NINJ2, ninjurin 2 |
计算分子量 | 142 aa, 16 kDa |
GenBank蛋白编号 | BC057766 |
基因名称 | NINJ2 |
Gene ID (NCBI) | 4815 |
RRID | AB_2881593 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q9NZG7 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
NINJ2 (Ninjurin2) is a member of the ninjurin family of adhesion molecules which mediate cell-to-cell and cell-to-extracellular matrix interactions during development, differentiation, and regeneration of the peripheral nervous system. The gene encodes NINJ2 is located on chromosome 12p13. NINJ2 mRNA is widely expressed in adult human tissues, with highest level in bone marrow, followed by peripheral leukocytes, lung, and lymph nodes. In the peripheral nervous system, NINJ2 is expressed constitutively in mature sensory and enteric neurons. The expression of NINJ2 is upregulated after nerve injury in Schwann cells, suggesting that it may promote nerve regeneration. It may also play an important role in the pathogenesis of inflammatory disorder. (PMID: 10627596)