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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 68709-1-Ig (same clone as 68709-1-PBS)

    WB analysis using 68709-1-Ig (same clone as 68709-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68709-1-Ig (NPTX2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68709-1-PBS in a different storage buffer formulation.

  • IF Staining of SH-SY5Y using 68709-1-Ig (same clone as 68709-1-PBS)

    IF Staining of SH-SY5Y using 68709-1-Ig (same clone as 68709-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using NPTX2 antibody (68709-1-Ig, Clone: 2H8D8 ) at dilution of 1:800 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (RGAM002). This data was developed using the same antibody clone with 68709-1-PBS in a different storage buffer formulation.

NPTX2 Monoclonal antibody, PBS Only

NPTX2 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 68709-1-PBS
CloneNo. 2H8D8

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat, pig, rabbit

Applications

WB, IF/ICC, Indirect ELISA

Synonyms

NP-II, NP2, Neuronal pentraxin-2, Neuronal pentraxin II, 2H8D8

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

68709-1-PBS targets NPTX2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.

Tested Applications WB, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat, pig, rabbit
Immunogen NPTX2 fusion protein Ag33808 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name neuronal pentraxin II
Synonyms NP-II, NP2, Neuronal pentraxin-2, Neuronal pentraxin II, 2H8D8
Calculated Molecular Weight 47 kDa
Observed Molecular Weight50-55 kDa
GenBank Accession NumberBC009924
Gene Symbol NPTX2
Gene ID (NCBI) 4885
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP47972
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Neuronal pentraxins constitute a family of proteins that are homologous to C-reactive protein (CRP) and serum amyloid P component (SAP), including NPTX1, NPTX2, and the neuronal pentraxin receptor (NPTXR). NPTX2, also known as NARP (neuronal activity-regulated pentaxin), is a secreted protein involved in excitatory synapse formation. It also plays a role in the clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. NPTX2 is highly up-regulated in Parkinson's disease (PD), suggesting it may be involved in the pathology of PD. (PMID: 12895424; 17987278; 10748068)