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Species Reactivity
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Species Reactivity
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Conjugate
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Conjugate
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Conjugate
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验证数据展示

  • WB analysis using 68291-1-Ig (same clone as 68291-1-PBS)

    WB analysis using 68291-1-Ig (same clone as 68291-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68291-1-Ig (NRCAM antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68291-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 68291-1-Ig (same clone as 68291-1-PBS)

    IF Staining of mouse brain using 68291-1-Ig (same clone as 68291-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using NRCAM antibody (68291-1-Ig, Clone: 2E1C3 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 68291-1-PBS in a different storage buffer formulation.

NRCAM Monoclonal antibody, PBS Only

NRCAM Monoclonal Antibody for WB, IF-P, Indirect ELISA
Cat No. 68291-1-PBS

产品说明书

CloneNo. 2E1C3

宿主/亚型

Mouse / IgG2b

种属反应性

Human, Mouse, Rat, Pig

应用

WB, IF-P, Indirect ELISA

别名

hBravo, KIAA0343, Neuronal surface protein Bravo, Ng CAM related, Nr CAM, NRCAM

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

68291-1-PBS targets NRCAM in WB, IF-P, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat, Pig samples.

经测试应用 WB, IF-P, Indirect ELISA Application Description
经测试反应性 Human, Mouse, Rat, Pig
免疫原 NRCAM fusion protein Ag20558 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 neuronal cell adhesion molecule
别名 hBravo, KIAA0343, Neuronal surface protein Bravo, Ng CAM related, Nr CAM, NRCAM
计算分子量 1304 aa, 144 kDa
观测分子量 130-140 kDa
GenBank蛋白编号BC098401
基因名称 NRCAM
Gene ID (NCBI) 4897
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ92823
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Neuronal cell adhesion molecule (NRCAM) is a member of the L1 subfamily of cell adhesion molecules (CAMs) that belong to the immunoglobulin superfamily (PMID: 11329126). NRCAM is a transmembrane protein composed of six Ig-like domains and five fibronectin type-III repeats in the extracellular region, with a highly conserved cytoplasmic tail. It is mainly expressed in the nervous system and is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. NRCAM is also expressed outside the nervous system. Altered expression of NRCAM has been associated with tumor progression in diverse organs (PMID: 22182708).