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NRCAM Recombinant antibody, PBS Only

NRCAM Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241862G1

Cat no : 84690-1-PBS

Print datasheet

Synonyms

Ng CAM related, Neuronal surface protein Bravo, neuronal cell adhesion molecule, KIAA0343, hBravo

验证数据展示

  • WB analysis of SH-SY5Y using 84690-1-RR (same clone as 84690-1-PBS)

    WB analysis of SH-SY5Y using 84690-1-RR (same clone as 84690-1-PBS)

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 84690-1-RR (NRCAM antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84690-1-PBS in a different storage buffer formulation.

  • WB analysis using 84690-1-RR (same clone as 84690-1-PBS)

    WB analysis using 84690-1-RR (same clone as 84690-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84690-1-RR (NRCAM antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84690-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84690-1-RR

    Affinity and Kinetic Characterization of 84690-1-RR

    Biolayer interferometry (BLl) kinetic assays of 84690-1-RR against Human NRCAM were performed. The affinity constant is below 1 pM.

产品信息

The immunogen of 84690-1-PBS is NRCAM Fusion Protein expressed in E. coli.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen NRCAM fusion protein Ag16237 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name neuronal cell adhesion molecule
Synonyms Ng CAM related, Neuronal surface protein Bravo, neuronal cell adhesion molecule, KIAA0343, hBravo
Calculated Molecular Weight 1304 aa, 144 kDa
Observed Molecular Weight144 kDa
GenBank Accession NumberBC098401
Gene Symbol NRCAM
Gene ID (NCBI) 4897
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ92823
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Neuronal cell adhesion molecule (NRCAM) is a member of the L1 subfamily of cell adhesion molecules (CAMs) that belong to the immunoglobulin superfamily (PMID: 11329126). NRCAM is a transmembrane protein composed of six Ig-like domains and five fibronectin type-III repeats in the extracellular region, with a highly conserved cytoplasmic tail. It is mainly expressed in the nervous system and is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. NRCAM is also expressed outside the nervous system. Altered expression of NRCAM has been associated with tumor progression in diverse organs (PMID: 22182708).