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NRG1, isoform SMDF Monoclonal antibody, PBS Only

NRG1, isoform SMDF Monoclonal Antibody for WB, IF/ICC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, pig, mouse, rat, rabbit

Applications

WB, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2C6D12

Cat no : 66492-1-PBS

Print datasheet

Synonyms

ARIA, GGF, GGF2, Glial growth factor, Heregulin, HGL, HRG, HRG1, HRGA, NDF, Neu differentiation factor, neuregulin 1, NRG1, Pro NRG1, SMDF

验证数据展示

  • WB analysis using 66492-1-Ig (same clone as 66492-1-PBS)

    WB analysis using 66492-1-Ig (same clone as 66492-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66492-1-Ig (NRG1, isoform SMDF antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 66492-1-PBS in a different storage buffer formulation.

  • IF Staining of MCF-7 using 66492-1-Ig (same clone as 66492-1-PBS)

    IF Staining of MCF-7 using 66492-1-Ig (same clone as 66492-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed MCF-7 cells using NRG1, isoform SMDF antibody (66492-1-Ig, Clone: 2C6D12 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66492-1-PBS in a different storage buffer formulation.

产品信息

66492-1-PBS targets NRG1, isoform SMDF in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, pig, mouse, rat, rabbit samples.

Tested Applications WB, IF/ICC, Indirect ELISA Application Description
Tested Reactivity Human, pig, mouse, rat, rabbit
Immunogen NRG1, isoform SMDF fusion protein Ag0803 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name neuregulin 1
Synonyms ARIA, GGF, GGF2, Glial growth factor, Heregulin, HGL, HRG, HRG1, HRGA, NDF, Neu differentiation factor, neuregulin 1, NRG1, Pro NRG1, SMDF
Calculated Molecular Weight 70 kDa
Observed Molecular Weight 70 kDa
GenBank Accession NumberBC007675
Gene Symbol NRG1
Gene ID (NCBI) 3084
RRIDAB_2881857
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ02297
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Neuregulin 1 (NRG1) is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by usage of different promoters and alternative splicing of a single gene. NRG1 and its receptor ErbB tyrosine kinase are expressed not only in the developing nervous system, but also in the adult brain. The antibody is specific to NRG1 isoform SMDF.